Results 251 to 260 of about 436,505 (303)

Long non-coding RNAs as key regulators of neurodegenerative protein aggregation. [PDF]

Alzheimers Dement
Xu Q, Liu D, Zhu LQ, Su Y, Huang HZ.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Massive experimental quantification allows interpretable deep learning of protein aggregation. [PDF]

Sci Adv
Thompson M, Martín M, Olmo TS, Rajesh C, Koo PK, Bolognesi B, Lehner B.   +6 more
europepmc   +1 more source

Dual mechanism of autophagy gene repression by PHF23 and therapeutic potential of its inhibition in protein aggregation disorders. [PDF]

Nucleic Acids Res
Choi SA, Kim J, Yu YS, Kim J, Kim SI, Bae H, Kwon J, Kim KI, Baek SH.   +8 more
europepmc   +1 more source

Uncovering the protein aggregation process through effect of G41D mutant SOD1 charge variation in ALS disease. [PDF]

Sci Rep
Waheed ZA, Colagar AH, Seyedalipour B, Baziyar P.   +3 more
europepmc   +1 more source

Submolecular Resolution of β‑Sheet Plasticity: Decoding Mutations and PTMs in Protein Aggregation Disorders. [PDF]

ACS Cent Sci
Wang R, Jian Z, Yang Y, Wang C, Yu L, Wang M, Wang C.   +6 more
europepmc   +1 more source

Machine learning-assisted screening of small-molecule drugs for suppressing protein aggregation and ROS generation based on ECL and CV dual-mode signals amplified by DNA. [PDF]

Chem Sci
Shi J, Zhu W, Yan J, Xiao C, Yao H, Meng L, Liu H, Mao L.   +7 more
europepmc   +1 more source

A Focus on the Link Between Metal Dyshomeostasis, Norepinephrine, and Protein Aggregation. [PDF]

Antioxidants (Basel)
Bacchella C, Capucciati A, Monzani E.
europepmc   +1 more source

Physicochemical Principles of Protein Aggregation

, 2013
This chapter provides a theoretical framework on the quantitative description of protein aggregation. The reader is provided with an overview of the fundamental theory of linear and helical polymers, as well as an introduction on the parameters governing evolution of aggregates over time.
Bolognesi B., Tartaglia G. G.
openaire   +3 more sources