Results 141 to 150 of about 2,270,992 (356)

ZeptoCTC - Sensitive Protein Analysis of True Single Cell Lysates using Reverse Phase Protein Arrays (RPPA) [PDF]

, 2023
Mahdi Rivandi, André Franken, Liwen Yang, Anna Abramova, Nadia Stamm, Jens Eberhardt, Berthold Gierke, Meike Beer, Tanja Fehm, Dieter Niederacher, Michael Pawlak, Hans Neubauer   +11 more
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Quantitative analysis of RNA-protein interactions on a massively parallel array for mapping biophysical and evolutionary landscapes

Nature Biotechnology, 2014
RNA-protein interactions drive fundamental biological processes and are targets for molecular engineering, yet quantitative and comprehensive understanding of the sequence determinants of affinity remains limited.
Jason D. Buenrostro, Lauren M. Chircus, C. Araya, Curtis J Layton, Howard Y. Chang, M. Snyder, W. Greenleaf   +6 more
semanticscholar   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

NIR Calibrations for Soybean Seeds and Soy Food Composition Analysis: Total Carbohydrates, Oil, Proteins and Water Contents [PDF]

, 2011
Conventional chemical analysis techniques are expensive, time consuming, and often destructive. The non-invasive Near Infrared (NIR) technology was introduced over the last decades for wide-scale, inexpensive chemical analysis of food and crop seed ...
I. C. Baianu, Jun Guo
core   +1 more source

Synthetic dosage lethal (SDL) interaction data of Hmt1 arginine methyltransferase

Data in Brief, 2020
The introduction of methyl groups on arginine residues is catalysed by Protein Arginine Methyltransferases (PRMTs). However, the regulatory mechanisms that dictate the levels of protein arginine methylation within cells are still not completely ...
Dimitris Kyriakou, Mamantia Constantinou, Antonis Kirmizis   +2 more
doaj  

Chemical-genetic profile analysis in yeast suggests that a previously uncharacterized open reading frame, YBR261C, affects protein synthesis

BMC Genomics, 2008
Background Functional genomics has received considerable attention in the post-genomic era, as it aims to identify function(s) for different genes. One way to study gene function is to investigate the alterations in the responses of deletion mutants to ...
Eroukova Veronika, Alamgir Md, Jessulat Matthew, Xu Jianhua, Golshani Ashkan   +4 more
doaj   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

Genetic interaction network of the Saccharomyces cerevisiae type 1 phosphatase Glc7

BMC Genomics, 2008
Background Protein kinases and phosphatases regulate protein phosphorylation, a critical means of modulating protein function, stability and localization.
Neszt Michael, Zadworny Megan, Por Hanting, Knockleby James, Szapiel Nicolas, Nguyen Thao, Logan Michael R, Harrison Paul, Bussey Howard, Mandato Craig A, Vogel Jackie, Lesage Guillaume   +11 more
doaj   +1 more source

Oligonucleotide array analysis of telomerase activation by the human papillomavirus type 16 E6 protein [PDF]

, 2001
Carol Duffy, Aloysius J. Klingelhutz
openalex   +1 more source