Results 221 to 230 of about 2,270,992 (356)

Protein-specific immune response elicited by the <i>Shigella sonnei</i> 1790GAHB GMMA-based candidate vaccine in adults with varying exposure to <i>Shigella</i>. [PDF]

mSphere
Randall AZ, Conti V, Nakakana U, Liang X, Teng AA, Di Pasquale AL, Kapulu M, Frenck R, Launay O, Ferruzzi P, Sciré AS, Marchetti E, Obiero C, Pablo JV, Edgar J, Bejon P, Shandling AD, Campo JJ, Yee A, Martin LB, Podda A, Micoli F.   +21 more
europepmc   +1 more source

Tri‐Layered Bioactive Cutaneous Scaffold with Integrated Bioactive Metal Organic Frameworks to Promote Full‐Thickness Infected Diabetic Wound Healing: Multifaceted Therapeutic Strategies

Advanced Healthcare Materials, EarlyView.
The limitations of existing clinical treatments highlight the need for a more comprehensive strategy for addressing infected diabetic wounds. A tri‐layered scaffold is developed to deliver therapeutics loaded in CuBDC and ZIF‐8 MOFs that are tailored to the requirements of deep‐infected diabetic wounds.
Ayse Gunyakti Mujtaba, Ayşe Karakeçili, Berna Topuz, Barış Batur, Okan Onar, Mehmet Eray Elçiğir, Çağdaş Oto, Alireza Hanifehnezhad, Kaan Orhan   +8 more
wiley   +1 more source

Characterization of small extracellular vesicles from ovarian cancer patients and pre-diagnostic patient samples: Evidence from the Danish blood donor study. [PDF]

PLoS One
Frisk NLS, Jørgensen MM, Bæk R, Atic AI, Brodersen TR, Ostrowski SR, Larsen MH, Posselt D, Høgdall E, Høgdall C, Pedersen OBV, Dalgaard LT.   +11 more
europepmc   +1 more source

Carbon‐Based Flexible Electrode for Efficient Electrochemical Generation of Reactive Chlorine Species in Tumor Therapy

Advanced Healthcare Materials, EarlyView.
A flexible electrode loaded with a carbon nanowire network (CC@C‐NWN) is developed for electrochemically generating reactive chlorine species (RCS) from abundant chloride ions in body fluids for tumor therapy. CC@C‐NWN enhances chlorine evolution, inducing redox dysregulation and synergistic apoptosis‐ferroptosis in tumor cells.
Cuinan Jiang, Zhaoyu Chen, Ruihao Yang, Ziga Luogu, Qian Ren, Hao Hu, Kaixin Wang, Senlin Li, Changlin Deng, Meng Li, Lu Zheng   +10 more
wiley   +1 more source

Multiplexed proteomic biosensor platform for label-free real-time simultaneous kinetic screening of thousands of protein interactions. [PDF]

Commun Biol
Agu CV, Cook RL, Martelly W, Gushgari LR, Mohan M, Takulapalli B.   +5 more
europepmc   +1 more source

Silicon Nanowire Mats Enable Advanced Bioelectrical Recordings in Primary DRG Cell Cultures

Advanced Healthcare Materials, EarlyView.
SiNW mat‐based MEA (NW_MEA) enables continuous intracellular recordings from neurons in primary rat DRG cell cultures, identifying C‐fiber nociceptors. Supported by an astrocyte feeder layer, SiNW mat promotes DRG neuron and glial cell growth, preserving in vivo‐like cell characteristics and allowing drug‐modulated activity monitoring.
Ivano Lucarini, Francesco Maita, Giorgia Conte, Emanuela Saracino, Francesco Formaggio, Elena Palmieri, Roberta Fabbri, Aikaterini Konstantoulaki, Chiara Lazzarini, Marco Caprini, Valentina Benfenati, Luca Maiolo, Annalisa Convertino   +12 more
wiley   +1 more source

Mapping Novel Copper-Regulated Signalling Pathways Using Antibody Arrays and in Silico Protein Network Analysis

, 2008
Aubrey R. White, Tingting Du, Laura Bica, Aphrodite Caragounis, KL Price, Gulay Filiz, Colin L. Masters, Kevin J. Barnham, Paul S. Donnelly, Victoria M. Perreau, Peter J. Crouch   +10 more
openalex   +1 more source

Room-temperature crystallography using a microfluidic protein crystal array device and its application to protein–ligand complex structure analysis

, 2020
Masatoshi Maeki, Shô Itô, Reo Takeda, Go Ueno, Akihiko Ishida, Hirofumi Tani, Masaki Yamamoto, Manabu Tokeshi   +7 more
openalex   +2 more sources

Biomimetic Scaffolds Enhance iPSC Astrocyte Progenitor Angiogenic, Immunomodulatory, and Neurotrophic Capacity in a Stiffness and Matrix‐Dependent Manner for Spinal Cord Repair Applications

Advanced Healthcare Materials, EarlyView.
Through tuning biomimetic scaffold stiffness and matrix composition the reparative capacity of astrocyte progenitors is enhanced. Soft, collagen‐IV/fibronectin‐functionalized scaffolds promote progenitor growth while improving angiogenic, immunomodulatory, and neurotrophic capacity in a stiffness and matrix‐dependent manner, demonstrating the impact of
Cian O'Connor, Ian Woods, Sarah F. McComish, Sean Kerr, Matthew McGrath, Juan Carlos Palomeque Chávez, Jack Maughan, Tara McGuire, Maeve A. Caldwell, Adrian Dervan, Fergal J. O'Brien   +10 more
wiley   +1 more source

Functional kinome profiling reveals brain protein kinase signaling pathways and gene networks altered by acute voluntary exercise in rats. [PDF]

PLoS One
Lee CM, Nguyen J, Pope B, Imami AS, Ryan VWG, Sahay S, Mathis V, Pulvender P, Eby HM, Arvay T, Alganem K, Wegman-Points L, McCullunsmith R, Yuan LL.   +13 more
europepmc   +1 more source