Results 301 to 310 of about 2,270,992 (356)

Genome-wide association mapping for heat shock tolerance in Mercenaria mercenaria through SNP microarray analysis. [PDF]

BMC Genomics
Yang H, Grouzdev D, Wang Z, Yee JC, Zeng Y, Sturmer L, Allam B.   +6 more
europepmc   +1 more source

MULTIPLEXED PROTEIN ARRAY PLATFORMS FOR ANALYSIS OF AUTOIMMUNE DISEASES [PDF]

Annual Review of Immunology, 2006
Several proteomics platforms have emerged in the past decade that show great promise for filling in the many gaps that remain from earlier studies of the genome and from the sequencing of the human genome itself. This review describes applications of proteomics technologies to the study of autoimmune diseases.
Michael G. Kattah, Atul J. Butte, Jessica D. Tenenbaum, Imelda Balboni, Paul J. Utz, Steven M. Chan   +5 more
openaire   +3 more sources

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Patterns of protein expression in infectious meningitis: A cerebrospinal fluid protein array analysis

Journal of Neuroimmunology, 2005
Seventy-nine cytokines, chemokines, and growth factors were measured by protein array analysis in the cerebrospinal fluid of patients with meningitis and controls. Several factors were found to be regulated, which have not been studied in the CNS before, e.g., macrophage inflammatory protein-1delta (CCL15) and neutrophil-activating peptide-2 (CXCL7 ...
Barbara Angele, Bernd Sporer, Uwe Koedel, Stefan Kastenbauer, Hans-Walter Pfister   +4 more
openaire   +3 more sources

Analysis of Autoantibody Profiles in Osteoarthritis Using Comprehensive Protein Array Concepts

Journal of Proteome Research, 2014
Osteoarthritis (OA) is the most common rheumatic disease and one of the most disabling pathologies worldwide. To date, the diagnostic methods of OA are very limited, and there are no available medications capable of halting its characteristic cartilage degeneration.
Cristina Ruiz-Romero, Lucía Lourido, Peter Nilsson, María González-González, Jochen M. Schwenk, Frauke Henjes, Francisco J. Blanco, Juan Fernández-Tajes, Manuel Fuentes   +8 more
openaire   +4 more sources

RPPApipe: A pipeline for the analysis of reverse-phase protein array data

Biosystems, 2014
Today, web-based data analysis pipelines exist for a wide variety of microarray platforms, such as ordinary gene-centered arrays, exon arrays and SNP arrays. However, most of the available software tools provide only limited support for reverse-phase protein arrays (RPPA), as relevant inherent properties of the corresponding datasets are not taken into
Eichner, Johannes; Heubach, Yvonne; Ruff, Manuel; Kohlhof, Hella; Strobl, Stefan; Mayer, Barbara; Pawlak, Michael; Templin, Markus F.; Zell, Andreas   +9 more
openaire   +4 more sources

Vertical nanowire arrays as a versatile platform for protein detection and analysis

Nanoscale, 2013
Protein microarrays are valuable tools for protein assays. Reducing spot sizes from micro- to nano-scale facilitates miniaturization of platforms and consequently decreased material consumption, but faces inherent challenges in the reduction of fluorescent signals and compatibility with complex solutions. Here we show that vertical arrays of nanowires (
Rostgaard, Katrine R., Frederiksen, Rune S., Liu, Yi-Chi, Berthing, Trine, Madsen, Morten H., Holm, Johannes, Nygård, Jesper, Martinez, Karen L.   +7 more
openaire   +4 more sources

Large-scale functional analysis using peptide or protein arrays

Nature Biotechnology, 2000
The array format for analyzing peptide and protein function offers an attractive experimental alternative to traditional library screens. Powerful new approaches have recently been described, ranging from synthetic peptide arrays to whole proteins expressed in living cells.
Gerard Cagney, Alia Qureshi Emili
openaire   +3 more sources

The Use of Electron Tomography for Structural Analysis of Disordered Protein Arrays

Journal of Structural Biology, 1997
A method based on Fourier transforms is described for obtaining a 3-D reconstruction from a paracrystalline object with static disorder. The method is derived from the standard methods used in 3-D reconstruction of 2-D crystals except that all of the Fourier coefficients are used and not just the sampled data from the periodic lattice.
Hanspeter Winkler, Kenneth A. Taylor, Jinghua Tang, Yifan Cheng   +3 more
openaire   +3 more sources