Results 311 to 320 of about 2,270,992 (356)

Stage-associated dynamic activity profile of transcription factors in nasopharyngeal carcinoma progression based on protein/DNA array analysis.

Omics, 2011
Transcription factors (TFs) are crucial modulators of gene regulation during the development and progression of tumors. We previously reported the activation of TFs in nasopharyngeal carcinoma (NPC) cell lines.
Bo Su, Hai-lin Tang, M. Deng, Q. Liao, Xi Zeng, Wen-ling Zhang, Bo Xiang, Li Wang, Xiao-Ling Li, Xia-Yu Li, Ming‐hua Wu, Gui-yuan Li   +11 more
semanticscholar   +1 more source

Protein array based interactome analysis of amyloid-β indicates an inhibition of protein translation.

Journal of Proteome Research, 2011
Oligomeric amyloid-β is currently of interest in amyloid-β mediated toxicity and the pathogenesis of Alzheimer's disease. Mapping the amyloid-β interaction partners could help to discover novel pathways in disease pathogenesis.
D. Virok, D. Simon, Z. Bozsó, R. Rajkó, Z. Datki, E. Balint, V. Szegedi, T. Janáky, B. Penke, L. Fülöp   +9 more
semanticscholar   +1 more source

Experimental Design & Analysis of Protein Array Data: Applying Methods from cDNA Arrays.

Blood, 2004
Abstract It appears that a number of recent manuscripts using protein microarray technology are using equivalent analysis procedures that the gene-expression microarray community implemented in their infancy. That is, utilizing a classic reference design such that the ratio of the sample of interest to a reference sample is the response ...
Irene M. Ghobrial, Antje Hoering, Jeanette E. Eckel   +2 more
openaire   +2 more sources

The Channel Array Interrogation (CAI) instrument for C-reactive protein analysis

2011 International Workshop on Biophotonics, 2011
A Channel Array Interrogation (CAI) instrument for multiparameter-analysis has been developed. In particular, the portable device was optimized for the C-reactive protein (CRP), one of the analytes of interest for sepsis.
AGiannetti, C Trono, F Baldini, L Bolzoni, G Porro   +4 more
openaire   +2 more sources

Genome-Wide Analysis of Protein-Protein Interactions Using a Two-Hybrid Array: Storage, Maintenance, and Working with Living Arrays

Cold Spring Harbor Protocols, 2006
INTRODUCTIONThe most difficult aspect of using an array approach for a high-throughput study is maintaining the array’s viability while avoiding contamination of the plates. This protocol describes three different storage methods for the array. Frozen stocks are the most permanent method and are an absolute requirement for maintaining a record of the ...
Tony R. Hazbun, John P. Miller
openaire   +3 more sources

Analysis of Protein Interactions with Immobilized Peptide Arrays Synthesized on Membrane Supports

Cold Spring Harbor Protocols, 2006
INTRODUCTIONThe following protocol describes the synthesis of short linear peptides, or peptide pools, on modified cellulose membranes, and the detection of their protein-binding partners. Peptides are synthesized from their carboxyl termini using Fmoc-amino acid derivatives.
Stefan Dübel, Ronald Frank
openaire   +3 more sources

Protein analysis by isoelectric focusing in a capillary array with an absorption imaging detector

Journal of Chromatography B: Biomedical Sciences and Applications, 1995
Isoelectric focusing (IEF) was successfully performed in capillary arrays with up to four capillaries. Separated proteins in the capillary array were detected by an UV absorption imaging detector. The whole analysis time for all samples in the capillary array was only 3 min due to the real-time imaging detector.
Janusz Pawliszyn, Jiaqi Wu
openaire   +3 more sources

Clustering and Network Analysis of Reverse Phase Protein Array Data

2017
Molecular profiling of proteins and phosphoproteins using a reverse phase protein array (RPPA) platform, with a panel of target-specific antibodies, enables the parallel, quantitative proteomic analysis of many biological samples in a microarray format.
openaire   +4 more sources

Protein chip array profiling analysis of sera from neuroblastoma patients

Cancer Letters, 2005
Neuroblastoma, the most common extracranial solid tumour in children, is characterised by highly heterogeneous clinical behaviour; patients are stratified into risk categories according to a combination of clinical and biological markers. However, identifying non-invasive prognostic markers predicting outcome independently from current risk ...
Alain Puisieux, Isabelle Iacono, Stéphanie Bréjon, D. Perol, Sylvie Negrier, Christophe Bergeron, Valérie Combaret   +6 more
openaire   +3 more sources

Analysis of protein tyrosine kinase expression in melanocytic lesions by tissue array

Journal of Cutaneous Pathology, 2003
Background:  It has been proposed that melanoma progression involves a multistep process from benign nevi (BN), dysplastic nevi (DN), radial and vertical growth phase melanoma (MM) to metastatic melanoma (MMM). Protein tyrosine kinases (PTKs) may participate in this progression.Methods:  Tissue microarray blocks of 89 melanocytic lesions were evaluated
Steven S. Shen, Omar Eton, Victor G. Prieto, Peter Zhang   +3 more
openaire   +3 more sources