Results 51 to 60 of about 2,014,238 (321)

Electronic biosensor arrays for label-free DNA and protein analysis [PDF]

, 2007
Stagni degli Esposti
openalex   +3 more sources

A functional proteogenomic analysis of endometrioid and clear cell carcinomas using reverse phase protein array and mutation analysis: protein expression is histotype-specific and loss of ARID1A/BAF250a is associated with AKT phosphorylation

BMC Cancer, 2014
BackgroundOvarian cancer is now recognized as a number of distinct diseases primarily defined by histological subtype. Both clear cell ovarian carcinomas (CCC) and ovarian endometrioid carcinomas (EC) may arise from endometriosis and frequently harbor ...
Kimberly C. Wiegand, B. Hennessy, S. Leung, Yemin Wang, Z. Ju, Mollianne J. McGahren, S. Kalloger, Sarah J. Finlayson, K. Stemke‐Hale, Yiling Lu, Fan Zhang, M. Anglesio, B. Gilks, G. Mills, D. Huntsman, M. Carey   +15 more
semanticscholar   +1 more source

Rare osteosarcoma cell subpopulation protein array and profiling using imaging mass cytometry and bioinformatics analysis

BMC Cancer, 2020
Background Single rare cell characterization represents a new scientific front in personalized therapy. Imaging mass cytometry (IMC) may be able to address all these questions by combining the power of MS-CyTOF and microscopy.
Izhar S. Batth, Qing Meng, Qi Wang, Keila E. Torres, Jared Burks, Jing Wang, Richard Gorlick, Shulin Li   +7 more
doaj   +1 more source

Proteomics, pathway array and signaling network-based medicine in cancer

Cell Division, 2009
Cancer is a multifaceted disease that results from dysregulated normal cellular signaling networks caused by genetic, genomic and epigenetic alterations at cell or tissue levels. Uncovering the underlying protein signaling network changes, including cell
Xu Hong, Liu Wei, Song Dong, Wu Josephine, Wang Libo, Wang Hongxia, Che Yufang, Zhao Xin, Liu Xiaoliang, Gao Ling, Ye Fei, Zhang David Y, Jiang Bo, Zhang Weijia, Wang Jinhua, Lee Peng   +15 more
doaj   +1 more source

A Metabolomics Investigation of the Metabolic Changes of Raji B Lymphoma Cells Undergoing Apoptosis Induced by Zinc Ions

Metabolites, 2021
Zinc plays a pivotal role in the function of cells and can induce apoptosis in various cancer cells, including Raji B lymphoma. However, the metabolic mechanism of Zn-induced apoptosis in Raji cells has not been explored.
Naeun Yoon, Hyunbeom Lee, Geonhee Lee, Eun Hye Kim, Seong Hwan Kim, Jeong-O Lee, Yunseon Song, Jinyoung Park, So-Dam Kim, Yeojin Kim, Byung Hwa Jung   +10 more
doaj   +1 more source

Bioinformatics analysis of mitochondrial encephalomyopathy with lactic acidemia and stroke⁃like episodes geneome microarray based on GEO database

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To investigate the possible pathogenesis and clinical feature of mitochondrial encephalomyopathy with lactic acidemia and stroke ⁃ like episodes (MELAS) on the molecular level by bioinformatics analysis of differential expression genes. Methods
Qian XU, Yang GAO, Lei LI, Jun YAN, Li⁃ling WANG, Tao⁃jie REN   +5 more
doaj  

Sex differences in global mRNA content of human skeletal muscle. [PDF]

PLoS ONE, 2009
Women oxidize more fat as compared to men during endurance exercise and several groups have shown that the mRNA content of selected genes related to fat oxidation are higher in women (e.g.
Amy C Maher, Minghua H Fu, Robert J Isfort, Alex R Varbanov, Xiaoyan A Qu, Mark A Tarnopolsky   +5 more
doaj   +1 more source

Screening a Protein Array with Synthetic Biotinylated Inorganic Polyphosphate To Define the Human PolyP-ome.

ACS Chemical Biology, 2018
Phenotypes are established by tight regulation on protein functions. This regulation can be mediated allosterically, through protein binding, and covalently, through post-translational modification (PTM).
Cristina Azevedo, Jyoti Singh, N. Steck, Alexandre Hofer, Felix A. Ruiz, Tanya Singh, H. Jessen, A. Saiardi   +7 more
semanticscholar   +1 more source

Synthetic dosage lethal (SDL) interaction data of Hmt1 arginine methyltransferase

Data in Brief, 2020
The introduction of methyl groups on arginine residues is catalysed by Protein Arginine Methyltransferases (PRMTs). However, the regulatory mechanisms that dictate the levels of protein arginine methylation within cells are still not completely ...
Dimitris Kyriakou, Mamantia Constantinou, Antonis Kirmizis   +2 more
doaj   +1 more source

New Insights into the Tumor Microenvironment Utilizing Protein Array Technology

International Journal of Molecular Sciences, 2018
The tumor microenvironment (TME) is a considerably heterogeneous niche, which is created by tumor cells, the surrounding tumor stroma, blood vessels, infiltrating immune cells, and a variety of associated stromal cells. Intercellular communication within
Wei Huang, S. Luo, R. Burgess, Yu-hua Yi, Gordon F. Huang, Ruo-Pan Huang   +5 more
semanticscholar   +1 more source