Results 141 to 150 of about 847,691 (346)

SMAD4 Loss Induces c-MYC-Mediated NLE1 Upregulation to Support Protein Biosynthesis, Colorectal Cancer Growth, and Metastasis. [PDF]

Cancer Res, 2022
Loevenich LP, Tschurtschenthaler M, Rokavec M, Silva MG, Jesinghaus M, Kirchner T, Klauschen F, Saur D, Neumann J, Hermeking H, Jung P.   +10 more
europepmc   +1 more source

Characterization of β-Ketoacyl-Acyl Carrier Protein Synthase III from Streptomyces glaucescens and Its Role in Initiation of Fatty Acid Biosynthesis [PDF]

, 1998
Lei Han, Sandra Lobo, Kevin A. Reynolds
openalex   +1 more source

Bioengineered Pancreatic Cancer Immunosuppressive Microenvironment Models for Screening Immunotherapies

Advanced Healthcare Materials, EarlyView.
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro, Margarida Henriques‐Pereira, Bruno M. Neves, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

Homology modeling of 3D structure of human chitinase-like protein CHI3L2

Open Life Sciences, 2010
Iershov Anton, Odynets Konstantin, Kornelyuk Alexander, Kavsan Vadim   +3 more
doaj   +1 more source

Red blood cell proteomics reveal remnant protein biosynthesis and folding pathways in PIEZO1-related hereditary xerocytosis. [PDF]

Front Physiol, 2022
Caulier A, Jankovsky N, Gautier EF, El Nemer W, Guitton C, Ouled-Haddou H, Guillonneau F, Mayeux P, Salnot V, Bruce J, Picard V, Garçon L.   +11 more
europepmc   +1 more source

The mungbean VrP locus encoding MYB90, an R2R3-type MYB protein, regulates anthocyanin biosynthesis

, 2022
Yun Lin, Kularb Laosatit, Jinyang Liu, Jingbing Chen, Xingxing Yuan, Prakit Somta, Xin Chen   +6 more
openalex   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

Glycodiversification of gentamicins through in vivo glycosyltransferase swapping enabled the creation of novel hybrid aminoglycoside antibiotics with potent activity and low ototoxicity

Acta Pharmaceutica Sinica B
Aminoglycosides (AGs) are a class of antibiotics with a broad spectrum of activity. However, their use is limited by safety concerns associated with nephrotoxicity and ototoxicity, as well as drug resistance.
Xinyun Jian, Cheng Wang, Shijuan Wu, Guo Sun, Chuan Huang, Chengbing Qiu, Yuanzheng Liu, Peter F. Leadlay, Dong Liu, Zixin Deng, Fuling Zhou, Yuhui Sun   +11 more
doaj   +1 more source

SERTAD1 Sensitizes Breast Cancer Cells to Doxorubicin and Promotes Lysosomal Protein Biosynthesis. [PDF]

Biomedicines, 2022
Nguyen HA, Vu SH, Jung S, Lee BS, Nguyen TNQ, Lee H, Lee HG, Myagmarjav D, Jo T, Choi Y, Lee MS.   +10 more
europepmc   +1 more source

Biosynthesis of Prostacyclin: Protein Structure and Gene Expression of Prostacyclin Synthase

, 1997
Toshihisa Hatae, Chieko Yokoyama, Shuntaro Hara, Tomoko Yabuki, Tadashi Tanabe   +4 more
openalex   +2 more sources