Results 11 to 20 of about 4,535,134 (266)

Enzymatic C‐to‐C Protein Ligation [PDF]

open access: yesAngewandte Chemie International Edition, 2022
AbstractTranspeptidase‐catalyzed protein and peptide modifications have been widely utilized for generating conjugates of interest for biological investigation or therapeutic applications. However, all known transpeptidases are constrained to ligating in the N‐to‐C orientation, limiting the scope of attainable products.
Fabian B. H. Rehm   +4 more
openaire   +5 more sources

Characterization of the blood coagulation system in morbidly obese patients [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2023
Obesity is a complex metabolic disorder that can be followed by blood coagulation disorders, athero­sclerosis and atherothrombosis. In the present work, the levels of fibrinogen, soluble fibrin, D-dimer as well as protein C were measured in the blood ...
D. S. Korolova   +5 more
doaj   +1 more source

Protein C in a patient with portal vein thrombosis in liver transplantation

open access: yesТрансплантология (Москва), 2021
Background. The problem of thromboses, including those associated with impaired hemostasis system, is relevant in orthotopic liver transplantation.Aim. To present the experience of intraoperative use of protein C during orthotopic liver transplantation ...
S. V. Zhuravel   +4 more
doaj   +1 more source

BSA nanoparticles loaded with IONPs for biomedical applications: fabrication optimization, physicochemical characterization and biocompatibility evaluation [PDF]

open access: yesNanomedicine Journal, 2019
Objective(s): Cancer diagnosis in its early stages of progress, can enhance the efficiency of treatment utilizing conventional therapy methods. Non-biocompatibility of iron oxide nanoparticles (IONPs) has made a big challenge against their usage as a ...
Parvin Najafi, Hasan Kouchakzadeh
doaj   +1 more source

Combined Parental Thrombophilia Gene Mutation Defects in Couples with Repeated Pregnancy Loss

open access: yesJournal of Human Reproductive Sciences, 2023
Background: Several genetic mutations in female thrombotic defects have recently been shown to affect recurrent pregnancy loss (RPL); however, it is unclear which common parental mutations are involved in thrombosis-associated repeated pregnancy loss RPL.
Mehdi Kashifard   +4 more
doaj   +1 more source

L-ARGININE AND L-GLUTAMIC ACID INCREASE THE CONTENT OF PROTEIN C IN THE EARLY STAGES OF ISOLATION FROM DONOR PLASMA [PDF]

open access: yesBiotechnologia Acta, 2021
Current large-scale production of blood-derived pharmacological preparations is aimed at expanding the list of products and deeper extraction of target proteins especially at the pre-purification stage.
I. I. Patalakh   +2 more
doaj   +1 more source

Evaluation of Some Plasma Coagulation Factors in Women with Spontaneous Miscarriage [PDF]

open access: yesInternational Journal of Fertility and Sterility, 2015
Background It has been reported that 15-20% of parous female have experienced at least one miscarriage, while 3% of them have experienced two miscarriages.
Mahsa Besharat   +5 more
doaj   +1 more source

Multidisciplinary approach to the diagnosis of disorders of coagulation system in childrenwith various pathologies

open access: yesЛечащий Врач, 2023
A significant problem in pediatrics is the hemostasisdysfunction, especially its anticoagulant system. The deficiency of fibrinolysis factors and the anticoagulant system increases the risk of thrombosis.
O. B. Gordeeva   +8 more
doaj   +1 more source

Cerebral venous sinus thrombosis

open access: yesJournal of the Scientific Society, 2023
Cerebral venous sinus thrombosis (CVST) is a relatively uncommon but important cause of stroke-like disease, accounting for fewer than 1% of all strokes. CVST is more common in females and infants.
Cyril Sajan   +5 more
doaj   +1 more source

Protein C in pneumonia [PDF]

open access: yesThorax, 2005
Pneumonia is characterised by a disturbed alveolar fibrin turnover which is the net result of activation of coagulation and attenuation of fibrinolysis.1,2 We have recently shown, in patients developing ventilator associated pneumonia (VAP), that suppression of fibrinolysis precedes the clinical diagnosis while procoagulant effects mainly occur ...
Choi, G   +5 more
openaire   +3 more sources

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