Results 21 to 30 of about 25,791,466 (309)

CHAPTER 1.1. Disulfide Bonds in Protein Folding and Stability [PDF]

open access: yes, 2018
Disulfide bonds are unique among post-translational modifications, as they add covalent crosslinks to the polypeptide chain. Accordingly, they can exert pronounced effects on protein folding and stability. This is of particular importance for secreted or
Sub Cellular Protein Chemistry   +7 more
core   +1 more source

Protein C Deficiency [PDF]

open access: yesArchives of Pathology & Laboratory Medicine, 2019
Protein C (PC) deficiency is a heritable or acquired risk factor for thrombophilia, with presentations varying from asymptomatic to venous thromboembolism to neonatal purpura fulminans, a life-threatening disorder. Hereditary PC deficiency is caused by mutation in the PC (PROC) gene located on chromosome 2q14.3.
Peyman, Dinarvand, Karen A, Moser
openaire   +2 more sources

Regulation and Dysregulation of Thrombin Activity

open access: yesSoutheastern European Medical Journal, 2021
Thrombin is the enzyme of the haemostasis system that stands at the crossroads between the coagulation cascade and coagulation inhibition by protein C, between plasma coagulation factors and cells involved in haemostasis and between haemostasis and the ...
Daria Korolova
doaj   +1 more source

C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2 [PDF]

open access: yes, 1998
Nek2 (for NIMA-related kinase 2) is a mammalian cell cycle-regulated kinase structurally related to the mitotic regulator NIMA of Aspergillus nidulans.
Fry, A. M.   +17 more
core   +1 more source

Protein C deficiency [PDF]

open access: yesIndian Journal of Hematology and Blood Transfusion, 2013
This report describes a 4 year old female child who presented with fever, pain and swelling of left leg following a trivial trauma. She was diagnosed as a case of deep vein thrombosis and subsequently found to be due to protein C deficiency.
Arun K, De   +3 more
openaire   +2 more sources

Neonatal Purpura Fulminans by an Unusual Pathogen: Elizabethkingia meningoseptica

open access: yesIndian Pediatrics Case Reports, 2022
Background: Neonatal purpura fulminans (PF) is a rare disorder characterized by the formation of dermal microvascular thrombosis associated with disseminated intravascular coagulation (DIC). It can be caused by inherited protein C or protein S deficiency
Rakesh Kumawat   +2 more
doaj   +1 more source

Covid-19 Enfeksiyonunda Anti-Trombin-3, Protein C ve Protein S Düzeylerinin İncelenmesi

open access: yesSakarya Tıp Dergisi, 2021
Amaç: SARS-CoV-2 virüsünün etkeni olduğu COVİD-19 enfeksiyonu salgın oluşturan önemli bir hastalıktır. COVİD-19 hastalarının birçoğunda kanama ve pıhtılaşma bozukluklarının geliştiği yapılan çalışmalarla gösterilmiştir.
Gizem Kılıçcıoğlu   +11 more
doaj   +1 more source

Electrospun Nanofibers and their Application in Tissue Repair and Engineering

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2020
Introduction: Tissue engineering is the repair and replacement of damaged tissues and requires a combination of cells, growth factor and porous scaffolds.
Sareh Arjmand   +3 more
doaj  

C-reactive Protein [PDF]

open access: yesJournal of Biological Chemistry, 2004
C-reactive protein (CRP) is a phylogenetically highly conserved plasma protein, with homologs in vertebrates and many invertebrates, that participates in the systemic response to inflammation. Its plasma concentration increases during inflammatory states, a characteristic that has long been employed for clinical purposes.
Steven, Black   +2 more
openaire   +2 more sources

Hsp90 Breaks the Deadlock of the Hsp70 Chaperone System [PDF]

open access: yes, 2018
Protein folding in the cell requires ATP-driven chaperone machines such as the conserved Hsp70 and Hsp90. It is enigmatic how these machines fold proteins.
Mayer, Matthias   +5 more
core   +2 more sources

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