Results 131 to 140 of about 3,609,148 (217)

Beta Cell Stress to Epitope Diversification: Post‐Translationally Modified Antigens in Type 1 Diabetes

Immunological Reviews, Volume 343, Issue 1, October 2026.
ABSTRACT Pancreatic beta cells are active participants in the loss of immune tolerance because their high secretory demand creates exceptional vulnerability to inflammatory exposure, endoplasmic reticulum (ER) stress, calcium dysregulation, and redox imbalance. These conditions can promote enzymatic and nonenzymatic changes in self‐proteins, generating
Megan L. Proffer, Saptarshi Roy, Jon D. Piganelli   +2 more
wiley   +1 more source

Determination of the degree of protein oxidation (carbonylation).

, 2014
Proteins were extracted from cells grown using either classical 2D flat culture techniques or as 3D microgravity spheroid techniques. a) OxyBlot detection of carbonylated proteins; b) loading control visualised with Coomassie Brilliant Blue total protein
Veit Schwämmle (460781), Krzysztof Wrzesinski (629691), Katarzyna Wojdyla (629696), Kira Eyd Joensen (629695), Vasco Botelho Carvalho (629697), Rattiyaporn Kanlaya (629693), Stephen J. Fey (629698), Jie Dai (54224), Adelina Rogowska-Wrzesinska (629692), Kamil Borkowski (629694)   +9 more
core   +1 more source

Integrated multitissue analysis reveals distinct oxidative stress responses during recovery from cold shock in the Amazonian fish Colossoma macropomum

Journal of Fish Biology, Volume 109, Issue 4, Page 2318-2331, October 2026.
Abstract Tambaqui (Colossoma macropomum) is a tropical fish widely cultivated in South America. The increasing demand for this species has heightened interest in its cultivation in subtropical regions with greater thermal variability, where cold shock may induce oxidative stress. This study evaluated the effects of cold shock and subsequent recovery on
Naiara Melo, Isaac Konig, Stefania Priscilla de Souza, Maria Fernanda Aquino Freitas, Daniella Aparecida de Jesus Paula, Ronald Kennedy Luz, Priscila Vieira Rosa, Luis David Solis Murgas   +7 more
wiley   +1 more source

Non-Invasive Redox Biomarkers Detected in Organ Preservation Outflow Solution Enable Early Prediction of Human Liver Allograft Dysfunction

Antioxidants
Liver transplantation is commonly used for end-stage liver disease, but the demand for organs exceeds the supply, leading to the use of expanded criteria donors (ECDs).
Daniel Vidal-Correoso, María José Caballero-Herrero, Ana M. Muñoz-Morales, Sandra V. Mateo, Marta Jover-Aguilar, Felipe Alconchel, Laura Martínez-Alarcón, Víctor López-López, Antonio Ríos-Zambudio, Pedro Cascales, José Antonio Pons, Pablo Ramírez, Kristine Stromsnes, Juan Gambini, Santiago Cuevas, Alberto Baroja-Mazo   +15 more
doaj   +1 more source

Novel Fluorometric Assay of Antiglycation Activity Based on Methylglyoxal-Induced Protein Carbonylation. [PDF]

Antioxidants (Basel), 2023
Koike S, Saito Y, Ogasawara Y.
europepmc   +1 more source

A cross‐species post‐translational modification profiling of histones by LC‐MS/MS revealed conserved oxidative modifications in plants

New Phytologist, Volume 252, Issue 2, Page 538-545, October 2026.
Conservation of post‐translational modifications (PTMs) in histones across six plant species.
Sau‐Shan Cheng, Wai‐Ching Sin, Yuen‐Yi Chau, Hon‐Ming Lam   +3 more
wiley   +1 more source

Extensive protein carbonylation precedes acrolein-mediated cell death in mouse hepatocytes

, 2001
Allyl alcohol hepatotoxicity is mediated by an alcohol dehydrogenase-derived biotranformation product, acrolein. This highly reactive ,-unsaturated aldehyde readily alkylates model proteins in vitro, forming, among other products, Michael addition ...
Burcham, Philip Cyril, Fontaine, Frank, Fontaine, Frank R., Burcham, Philip C.   +3 more
core   +1 more source

Antifungal Mechanism Effect of Artemisinin on Fusarium solani

Pharmaceuticals
Background: Fusarium solani (Fs), a drug-resistant phytopathogenic fungus, is a major cause of severe infections in both plants and humans. Artemisia annua and its derivatives exhibit antimicrobial, antiviral and anticholesterolemic activities, yet their
César Espinoza, Francisco Roberto Quiroz-Figueroa, Oswaldo Guzmán-López, Eliel Ruiz-May, Verónica Gallegos-García, Alejandro Salinas-Castro, Giovanny García-Serrano, Thuluz Meza-Menchaca   +7 more
doaj   +1 more source

Protein Carbonylation and Glycation in Human Lenses

Collegium antropologicum, 2002
It has been observed protein carbonylation and glycation in the lens epithelial cell fractions of lenses in people with mature cataract. We used lenses of diabetic patients, weak and strong cigarette smokers and people who had senile cataract. The protein glycation is the highest in a diabetic senile cataract patients and the lowest in non-diabetic ...
Balog, Zlatko, Klepac, Ratomir, Šikić, Jakov, Jukić- Lešina, Tanja   +3 more
openaire   +3 more sources

Influence of Protein Carbonylation on Human Adipose Tissue Dysfunction in Obesity and Insulin Resistance. [PDF]

Biomedicines, 2022
Navarro-Ruiz MC, Soler-Vázquez MC, Díaz-Ruiz A, Peinado JR, Nieto Calonge A, Sánchez-Ceinos J, Tercero-Alcázar C, López-Alcalá J, Rangel-Zuñiga OA, Membrives A, López-Miranda J, Malagón MM, Guzmán-Ruiz R.   +12 more
europepmc   +1 more source