Results 191 to 200 of about 6,508,178 (232)

Elevated Levels of Protein Carbonylation in Patients With Diabetic Nephropathy: Therapeutic and Diagnostic Prospects.

American Journal of the Medical Sciences, 2019
BACKGROUND Oxidative stress-induced protein oxidation has been reported in diabetes mellitus; however a relationship between protein carbonylation and diabetic nephropathy remains to be determined.
E. Almogbel, Naila Rasheed
semanticscholar   +1 more source

Protein carbonyl groups in trained subjects

Clinical Hemorheology and Microcirculation, 2012
The purpose of this research was to evaluate the plasma protein carbonyl groups (PC) in 81 trained subjects (TS) who practiced regular, non professional physical activity. They were divided into three groups according to the type of sport they practiced (endurance, mixed or power).
LO PRESTI, Rosalia, CANINO, Baldassare, Montana, M, CALANDRINO, Vincenzo, CAIMI, Gregorio   +4 more
openaire   +3 more sources

Protein carbonylation in dopaminergic cells exposed to rotenone.

Toxicology Letters, 2019
Rotenone is an environmental neurotoxin that induces degeneration of dopaminergic neurons and the most common features of Parkinson's disease in animal models.
E. Chiaradia, G. Renzone, A. Scaloni, M. Caputo, E. Costanzi, A. Gambelunghe, G. Muzi, L. Avellini, C. Emiliani, S. Buratta   +9 more
semanticscholar   +1 more source

Spectrophotometric Analysis of Protein Carbonyls

2022
Oxidation of proteins is a major threat to their functionality and to the sensory properties and nutritional value of meat and meat products. Moreover, the intake of protein oxidation products may also involve a potential health risk for consumers. The accurate analysis of food protein oxidation seems to be an issue of scientific and technological ...
Francesca Soglia, Giulia Baldi, Alberto Gonzalez-Mohino, Silvia Dıaz-Velasco, Massimiliano Petracci, Mario Estevez   +5 more
openaire   +2 more sources

Protein Carbonyl Formation in the Diaphragm

American Journal of Respiratory Cell and Molecular Biology, 2005
Although protein carbonyl formation is an index of oxidative stress in skeletal muscles, the exact proteins, which undergo oxidation in these muscles, remain unknown. We used 2D electrophoresis, immunoblotting, and mass spectrometry to identify carbonylated proteins in the diaphragm in septic animals.
Esther, Barreiro, Joaquim, Gea, Marcos, Di Falco, Leonid, Kriazhev, Susan, James, Sabah N A, Hussain   +5 more
openaire   +2 more sources

Protein Carbonylation in Plants

2017
This chapter provides an overview of the current knowledge on protein carbonylation in plants and its role in plant physiology. It starts with a brief outline of the turnover and production sites of reactive oxygen species (ROS) in plants and the causes of protein carbonylation.
Møller, Ian Max, Havelund, Jesper, Rogowska-Wrzesinska, Adelina   +2 more
openaire   +2 more sources

Profiling Carbonylated Proteins in Human Plasma

Journal of Proteome Research, 2010
This study reports the first proteomic-based identification and characterization of oxidized proteins in human plasma. The study was conducted by isolating carbonylated proteins from the plasma of male subjects (age 32-36) with avidin affinity chromatography subsequent to biotinylation of carbonyl groups with biotin hydrazide and sodium ...
Ashraf G, Madian, Fred E, Regnier
openaire   +2 more sources

Carbonyl Stress: Increased Carbonyl Modification of Tissue and Cellular Proteins in Uremia

Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 1999
Advanced glycation end-products (AGEs) are formed during non enzymatic glycation and oxidation (glycoxidation) reactions. This process is accelerated in diabetics owing to hyperglycemia, and it has been implicated in the pathogenesis of diabetic complications.
T, Miyata, Y, Izuhara, H, Sakai, K, Kurokawa   +3 more
openaire   +2 more sources

Microfluidic Carbonylated Protein Capture

2013
We report a proof of principle study for the use of oxalyldihydrazide as a crosslinker for enrichment of carbonylated proteins within a microfluidic chip. Surface modification steps are characterized and analyzed using analytical techniques. We use in vitro oxidized bovine serum albumin as a model protein for testing the selectivity and specificity of ...
Bryant C. Hollins, Steven A. Soper, June Feng   +2 more
openaire   +1 more source

Glucocorticoids Increase Protein Carbonylation and Mitochondrial Dysfunction

Hormone and Metabolic Research, 2013
Many major psychiatric illnesses have been associated with excessive and prolonged release of glucocorticoid stress hormones potentially leading to deleterious neuronal effects. Recent studies have suggested that oxidative stress is associated with psychiatric illnesses.
Tang, V M, Young, A H, Tan, H, Beasley, C, Wang, J-F   +4 more
openaire   +3 more sources