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Protein conformation and biomolecular condensates [PDF]
Protein conformation and cell compartmentalization are fundamental concepts and subjects of vast scientific endeavors. In the last two decades, we have witnessed exciting advances that unveiled the conjunction of these concepts.
Diego S. Vazquez+3 more
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Protein conformation in a vaccine matters. [PDF]
Vaccination is one of the most successful public health measures for control of viral diseases. Indeed, vaccines have either eliminated or considerably reduced many viral diseases worldwide. However, there are still many serious viral pathogens for which no vaccine is available. One of these pathogens is respiratory syncytial virus (RSV).
Morrison TG.
europepmc +4 more sources
Exploring the conformational diversity of proteins [PDF]
An artificial intelligence-based method can predict distinct conformational states of membrane transporters and receptors.
Avner Schlessinger, Massimiliano Bonomi
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Monoclonal Antibodies as Probes to Study Ligand-Induced Conformations of Troponin Subunits
Striated muscle contraction and relaxation is regulated by Ca2+ at the myofilament level via conformational modulations of the troponin complex. To understand the structure–function relationship of troponin in normal muscle and in myopathies, it is ...
Monica Rasmussen+2 more
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Conformations of Proteins in Equilibrium [PDF]
6 pages, 3 eps ...
Micheletti, Cristian+2 more
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Insights into the conformational organization and dynamics of proteins complexes at membranes is essential for our mechanistic understanding of numerous key biological processes.
Nadia Füllbrunn+11 more
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Amyloid structures assemble through a repeating type of bonding called “cross-β”, in which identical sequences in many protein molecules form β-sheets that interdigitate through side chain interactions.
Peter N. Lipke+3 more
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Cerium oxide (CeO2) nanoparticles are expected to have applications in the biomedical field because of their antioxidative properties. Inorganic nanoparticles interact with proteins at the nanoparticle surface and change their conformation when ...
Masakazu Umezawa+4 more
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Excitatory-inhibitory (E-I) imbalance has been shown to contribute to the pathogenesis of a wide range of neurodevelopmental disorders including autism spectrum disorders, epilepsy, and schizophrenia.
Kelvin K. Hui+5 more
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De novo protein synthesis by the ribosome and its multitude of co-factors must occur in a tightly regulated manner to ensure that the correct proteins are produced accurately at the right time and, in some cases, also in the proper location.
Kelvin K. Hui+3 more
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