Results 1 to 10 of about 728,141 (364)
Protein conformation and biomolecular condensates. [PDF]
Curr Res Struct Biol, 2022 Protein conformation and cell compartmentalization are fundamental concepts and subjects of vast scientific endeavors. In the last two decades, we have witnessed exciting advances that unveiled the conjunction of these concepts. An avalanche of studies highlighted the central role of biomolecular condensates in membraneless subcellular ...
Vazquez DS +3 more
europepmc +5 more sources
Cooperative Gating and Spatial Organization of Membrane Proteins through Elastic Interactions [PDF]
, 2007 Biological membranes are elastic media in which the presence of a transmembrane protein leads to local bilayer deformation. The energetics of deformation allow two membrane proteins in close proximity to influence each other's equilibrium conformation ...
Andrej Sali +4 more
core +10 more sources
Protein conformation in a vaccine matters. [PDF]
Oncotarget, 2015 Vaccination is one of the most successful public health measures for control of viral diseases. Indeed, vaccines have either eliminated or considerably reduced many viral diseases worldwide. However, there are still many serious viral pathogens for which no vaccine is available. One of these pathogens is respiratory syncytial virus (RSV).
Morrison TG.
europepmc +4 more sources
Exploring the conformational diversity of proteins [PDF]
eLife, 2022 An artificial intelligence-based method can predict distinct conformational states of membrane transporters and receptors.
Avner Schlessinger, Massimiliano Bonomi
openaire +4 more sources
Conformations of Proteins in Equilibrium [PDF]
Physical Review Letters, 2001 6 pages, 3 eps ...
Micheletti, Cristian +2 more
openaire +4 more sources
Mechano-transduction: from molecules to tissues. [PDF]
, 2014 External forces play complex roles in cell organization, fate, and homeostasis. Changes in these forces, or how cells respond to them, can result in abnormal embryonic development and diseases in adults.
Dunn, Alexander R +3 more
core +2 more sources
Protein Adsorption and Conformational Changes [PDF]
Molecules, 2021 Protein adsorption onto surfaces of diverse materials of both natural and artificial origin is of utmost relevance in many areas of research and technology: medicine, pharmaceutical sciences, analytical sciences, biotechnology, nanotechnology, and cell biology, among others [...]
openaire +3 more sources
Population Shuffling of Protein Conformations [PDF]
Angewandte Chemie, 2014 AbstractMotions play a vital role in the functions of many proteins. Discrete conformational transitions to excited states, happening on timescales of hundreds of microseconds, have been extensively characterized. On the other hand, the dynamics of the ground state are widely unexplored.
Claudia Schwiegk +9 more
openaire +5 more sources
Pyrene: A Probe to Study Protein Conformation and Conformational Changes [PDF]
Molecules, 2011 The review focuses on the unique spectral features of pyrene that can be utilized to investigate protein structure and conformation. Pyrene is a fluorescent probe that can be attached covalently to protein side chains, such as sulfhydryl groups. The spectral features of pyrene are exquisitely sensitive to the microenvironment of the probe: it exhibits ...
Vasanthy Narayanaswami +2 more
openaire +4 more sources