Results 1 to 10 of about 6,671,171 (389)
Genome-wide Translation Profiling by Ribosome-Bound tRNA Capture
Cell Reports, 2018 Summary: In the ribosome complex, tRNA is a critical element of mRNA translation. A rich repertoire of cell regulation is hypothesized to occur during the recruitment of specific tRNAs in polypeptide formation.
Chien-Wen Chen, Motomasa Tanaka
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Pathogens, 2021 Amyloid structures assemble through a repeating type of bonding called “cross-β”, in which identical sequences in many protein molecules form β-sheets that interdigitate through side chain interactions.
Peter N. Lipke +3 more
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Conformational kinetics reveals affinities of protein conformational states [PDF]
Proceedings of the National Academy of Sciences, 2015 Significance Despite 50 years of studies of coupled binding and conformational change reactions in proteins and nucleic acids, there has been no detailed analysis of the affinities of the multiple conformational states involved. The relationship between these affinities and the dynamics of conformational change has also been largely ...
Daniels, Kyle G +2 more
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Frontiers in Toxicology, 2023 Cerium oxide (CeO2) nanoparticles are expected to have applications in the biomedical field because of their antioxidative properties. Inorganic nanoparticles interact with proteins at the nanoparticle surface and change their conformation when ...
Masakazu Umezawa +4 more
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Conformations of Proteins in Equilibrium [PDF]
Physical Review Letters, 2001 6 pages, 3 eps ...
Micheletti, Cristian +2 more
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Aβ Secretion and Plaque Formation Depend on Autophagy
Cell Reports, 2013 Alzheimer’s disease (AD) is a neurodegenerative disease biochemically characterized by aberrant protein aggregation, including amyloid beta (Aβ) peptide accumulation. Protein aggregates in the cell are cleared by autophagy, a mechanism impaired in AD. To
Per Nilsson +9 more
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Limited proteolysis in the investigation of beta2-microglobulin amyloidogenic and fibrillar states. [PDF]
, 2005 Amyloid fibrils of patients treated with regular haemodialysis essentially consists of β2-microglobulin (β2-m) and its truncated species ΔN6β2-m lacking six residues at the amino terminus.
AMORESANO, ANGELA +4 more
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Cooperative Gating and Spatial Organization of Membrane Proteins through Elastic Interactions [PDF]
, 2007 Biological membranes are elastic media in which the presence of a transmembrane protein leads to local bilayer deformation. The energetics of deformation allow two membrane proteins in close proximity to influence each other's equilibrium conformation ...
Andrej Sali +4 more
core +5 more sources
CHIMIA, 2011 The biological properties of a protein critically depend on its conformation, which can vary as a result of changes in conditions such as pH or following the addition of various substances.
Denis Prim +2 more
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Sequence-Dependent Correlated Segments in the Intrinsically Disordered Region of ChiZ
Biomolecules, 2020 How sequences of intrinsically disordered proteins (IDPs) code for their conformational dynamics is poorly understood. Here, we combined NMR spectroscopy, small-angle X-ray scattering (SAXS), and molecular dynamics (MD) simulations to characterize the ...
Alan Hicks +3 more
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