Chronic Wasting Disease (CWD) in Cervids and the Consequences of a Mutable Protein Conformation. [PDF]
ACS Omega, 2022 Silva CJ.
europepmc +1 more source
PK Changes of Ionizable Reporter Groups as an Index of Conformational Changes in Proteins. A Study of Fluorescein-Labelled Ribonuclease A [PDF]
, 1976 Jean‐Renaud Garel
openalex +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Detecting Differences in Prion Protein Conformation by Quantifying Methionine Oxidation. [PDF]
ACS Omega, 2022 Silva CJ, Erickson-Beltran M.
europepmc +1 more source
Analysis of the code relating sequence to conformation in globular proteins. An informational analysis of the role of the residue in determining the conformation of its neighbours in the primary sequence [PDF]
, 1974 Barry Robson, Roger H. Pain
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Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Atomic Structure of the Human Sapovirus Capsid Reveals a Unique Capsid Protein Conformation in Caliciviruses. [PDF]
J Virol, 2022 Miyazaki N +7 more
europepmc +1 more source
Molecular dynamics as an approach to study prion protein misfolding and the effect of pathogenic mutations [PDF]
, 2011 Daggett, Valerie, van der Kamp, Marc W
core +1 more source