Results 1 to 10 of about 102,994 (159)

Status and perspective of protein crystallography at the first multi-bend achromat based synchrotron MAX IV. [PDF]

J Synchrotron Radiat
The first multi-bend achromat based synchrotron MAX IV operates two protein crystallography beamlines, BioMAX and MicroMAX. BioMAX is designed as a versatile, stable, high-throughput beamline catering for most protein crystallography experiments ...
Gonzalez A, Krojer T, Nan J, Bjelčić M, Aggarwal S, Gorgisyan I, Milas M, Eguiraun M, Casadei C, Chenchiliyan M, Jurgilaitis A, Kroon D, Ahn B, Ekström JC, Aurelius O, Lang D, Ursby T, Thunnissen MMGM.   +17 more
europepmc   +2 more sources

Emerging Topics in Protein Crystallography. [PDF]

Int J Mol Sci
Protein crystallography is the discipline concerned with the determination of the three-dimensional structure of biological macromolecules in a crystalline state [...]
Chen Z, Zanotti G.
europepmc   +3 more sources

50th anniversary of the Stanford SSRL synchrotron radiation and protein crystallography initiative. [PDF]

J Synchrotron Radiat
We provide a historical introduction spanning the past 50 years of synchrotron radiation protein crystallography. We then provide a resume of current trends.
Helliwell JR, Nave C, Szebenyi DM.
europepmc   +2 more sources

Progress in protein crystallography. [PDF]

Protein Pept Lett, 2016
Macromolecular crystallography evolved enormously from the pioneering days, when structures were solved by "wizards" performing all complicated procedures almost by hand. In the current situation crystal structures of large systems can be often solved very effectively by various powerful automatic programs in days or hours, or even minutes.
Dauter Z, Wlodawer A.
europepmc   +3 more sources

Cryo-EM structure of a functional monomeric Photosystem I from Thermosynechococcus elongatus reveals red chlorophyll cluster

Communications Biology, 2021
Çoruh, Frank et al. report the structure of monomeric Photosystem I from cyanobacteria Thermosynechoccocus elongatus BP-1. They assign monomerization-induced loss of red chlorophylls to a cluster of chlorophylls adjacent to PsaX.
Orkun Çoruh, Anna Frank, Hideaki Tanaka, Akihiro Kawamoto, Eithar El-Mohsnawy, Takayuki Kato, Keiichi Namba, Christoph Gerle, Marc M. Nowaczyk, Genji Kurisu   +9 more
doaj   +1 more source

Infrared protein crystallography [PDF]

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2011
We consider the application of infrared spectroscopy to protein crystals, with particular emphasis on exploiting molecular orientation through polarization measurements on oriented single crystals. Infrared microscopes enable transmission measurements on individual crystals using either thermal or nonthermal sources, and can accommodate flow cells ...
Sage, J. Timothy, Zhang, Yunbin, McGeehan, John, Ravelli, Raimond B. G., Weik, Martin, Van Thor, Jasper J.   +5 more
openaire   +5 more sources

Structure of cyanobacterial photosystem I complexed with ferredoxin at 1.97 Å resolution

Communications Biology, 2022
In order to aid the understanding of the electron transfer process within the cyanobacterial photosystem I, its structure - when complexed with Ferredoxin - is determined at 1.97 Å resolution.
Jiannan Li, Noriyuki Hamaoka, Fumiaki Makino, Akihiro Kawamoto, Yuxi Lin, Matthias Rögner, Marc M. Nowaczyk, Young-Ho Lee, Keiichi Namba, Christoph Gerle, Genji Kurisu   +10 more
doaj   +1 more source

Self-Assembling Protein Nanoparticles in the Design of Vaccines: 2022 Update

Vaccines, 2022
Vaccines constitute a pillar in the prevention of infectious diseases. The unprecedented emergence of novel immunization strategies due to the COVID-19 pandemic has again positioned vaccination as a pivotal measure to protect humankind and reduce the ...
Sergio Morales-Hernández, Nerea Ugidos-Damboriena, Jacinto López-Sagaseta   +2 more
doaj   +1 more source

Functional Importance of the Hydrophobic Residue 362 in Influenza A PB1 Subunit

Viruses, 2023
PB1, acting as the catalytic subunit of the influenza polymerase, has numerous sequentially and structurally conserved regions. It has been observed that the slight modification of residues in PB1 would greatly affect the polymerase activity and even ...
Johnson Jor-Shing Chan, Yun-Sang Tang, Chun-Yeung Lo, Pang-Chui Shaw   +3 more
doaj   +1 more source

GRB2 dimerization mediated by SH2 domain-swapping is critical for T cell signaling and cytokine production

Scientific Reports, 2023
GRB2 is an adaptor protein required for facilitating cytoplasmic signaling complexes from a wide array of binding partners. GRB2 has been reported to exist in either a monomeric or dimeric state in crystal and solution.
Aline Sandouk, Zhen Xu, Sankar Baruah, Mikaela Tremblay, Jesse B. Hopkins, Srinivas Chakravarthy, Lokesh Gakhar, Nicholas J. Schnicker, Jon C. D. Houtman   +8 more
doaj   +1 more source