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Protein design with fragment databases

Current Opinion in Structural Biology, 2011
Structure-based computational methods are popular tools for designing proteins and interactions between proteins because they provide the necessary insight and details required for rational engineering. Here, we first argue that large-scale databases of fragments contain a discrete but complete set of building blocks that can be used to design ...
Erik, Verschueren   +5 more
openaire   +2 more sources

Databases of Protein–Protein Interactions and Complexes

2009
In the current understanding, translation of genomic sequences into proteins is the most important path for realization of genome information. In exercising their intended function, proteins work together through various forms of direct (physical) or indirect interaction mechanisms.
Hong Sain, Ooi   +5 more
openaire   +2 more sources

Searching the protein sequence database

Bulletin of Mathematical Biology, 1984
As the volume of protein sequence data grows, rapid methods for searching the protein sequence database become of primary importance. Rigorous comparison of sequences is obtained with the well-known dynamic programming algorithms. However, these algorithms are not rapid enough to use for routinely searching the entire database. In this paper we discuss
B C, Orcutt, W C, Barker
openaire   +2 more sources

Software and Databases for Protein–Protein Docking

Protein-protein interactions (PPIs) provide valuable insights for understanding the principles of biological systems and for elucidating causes of incurable diseases. One of the techniques used for computational prediction of PPIs is protein-protein docking calculations, and a variety of software has been developed.
Małgorzata, Jarończyk   +2 more
openaire   +2 more sources

Protein Function Database as a Deductive and Object-Oriented Database

1991
This paper describes an experiment on a knowledge base approach to molecular biological databases, especially focusing on a protein function database.
openaire   +1 more source

Protein Superfamily Database (Prosup)

1996
We have constructed a protein superfamily database (PROSUP). Amino acid sequences belonging to the protein superfamilies defined by PIR International are quantified by application of principal component analysis on the basis of the physicochemical properties of amino acid residues.
Katsuhisa Horimoto   +3 more
openaire   +1 more source

The protein disease database

ELECTROPHORESIS, 1995
P F, Lemkin   +6 more
openaire   +2 more sources

Protein-to-protein interactions

ACM Computing Surveys, 2010
Mario Cannataro   +2 more
exaly  

Use of mass spectrometry-derived data to annotate nucleotide and protein sequence databases

Trends in Biochemical Sciences, 2001
Matthias Mann, Akhilesh Pandey
exaly  

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