Results 41 to 50 of about 4,646,061 (279)
Evaluating deterministic motif significance measures in protein databases
Algorithms for Molecular Biology, 2007 Background Assessing the outcome of motif mining algorithms is an essential task, as the number of reported motifs can be very large. Significance measures play a central role in automatically ranking those motifs, and therefore alleviating the analysis ...
Azevedo Paulo J, Ferreira Pedro
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Frontiers in Molecular Biosciences, 2021 Human genome resequencing projects provide an unprecedented amount of data about single-nucleotide variations occurring in protein-coding regions and often leading to observable changes in the covalent structure of gene products.
Castrense Savojardo +4 more
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Improving classification in protein structure databases using text mining
BMC Bioinformatics, 2009 Background The classification of protein domains in the CATH resource is primarily based on structural comparisons, sequence similarity and manual analysis.
Jones David T +2 more
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Protein Bioinformatics Databases and Resources [PDF]
, 2010 In the past decades, a variety of publicly available data repositories and resources have been developed to support protein related information management, data-driven hypothesis generation and biological knowledge discovery. However, there is also an increasing confusion for the researchers who are trying to quickly find the appropriate resources to ...
Chuming, Chen +2 more
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Studying protein-protein interactions using peptide arrays [PDF]
, 2010 Screening of arrays and libraries of compounds is well-established as a high-throughput method for detecting and analyzing interactions in both biological and chemical systems. Arrays and libraries can be composed from various types of molecules, ranging
Rito, T. +7 more
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The PIR integrated protein databases and data retrieval system
Data Science Journal, 2006 The Protein Information Resource (PIR) provides many databases and tools to support genomic and proteomic research. PIR is a member of UniProt—Universal Protein Resource—the central repository of protein sequence and function, which maintains UniProt ...
H Huang, ZZ Hu, BE Suzek, CH Wu
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Comparative Assessment of Protein Kinase Inhibitors in Public Databases and in PKIDB
Molecules, 2020 Since the first approval of a protein kinase inhibitor (PKI) by the Food and Drug Administration (FDA) in 2001, 55 new PKIs have reached the market, and many inhibitors are currently being evaluated in clinical trials.
Colin Bournez +6 more
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BMC Bioinformatics, 2007 Background Each major protein database uses its own conventions when assigning protein identifiers. Resolving the various, potentially unstable, identifiers that refer to identical proteins is a major challenge.
Leinonen Rasko +8 more
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The Pfam protein families database [PDF]
Nucleic Acids Research, 2009 Pfam is a widely used database of protein families and domains. This article describes a set of major updates that we have implemented in the latest release (version 24.0). The most important change is that we now use HMMER3, the latest version of the popular profile hidden Markov model package.
Robert D. Finn +13 more
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DisProt: the Database of Disordered Proteins [PDF]
Nucleic Acids Research, 2007 The Database of Protein Disorder (DisProt) links structure and function information for intrinsically disordered proteins (IDPs). Intrinsically disordered proteins do not form a fixed three-dimensional structure under physiological conditions, either in their entireties or in segments or regions.
Megan Sickmeier +11 more
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