Protective Effect of Bergapten against Human Erythrocyte Hemolysis and Protein Denaturation In Vitro [PDF]
International Journal of Inflammation, 2021 Bergapten, a furocoumarin found in many medicinal plants, is used for the management of various conditions. The present in vitro study evaluated the ability of bergapten to prevent human erythrocyte hemolysis and protein denaturation.
Douglas Bosco Aidoo +3 more
doaj +3 more sources
Mechanisms of Change in Emulsifying Capacity Induced by Protein Denaturation and Aggregation in Quick-Frozen Pork Patties with Different Fat Levels and Freeze–Thaw Cycles [PDF]
Foods, 2021 Herein, we discuss changes in the emulsifying properties of myofibrillar protein (MP) because of protein denaturation and aggregation from quick-frozen pork patties with multiple fat levels and freeze–thaw (F–T) cycles.
Nan Pan +7 more
doaj +3 more sources
In-Vial Detection of Protein Denaturation Using Intrinsic Fluorescence Anisotropy. [PDF]
Anal Chem, 2023 The conventional quality control techniques for identifying the denaturation of biopharmaceuticals includes sodium dodecyl sulfate-polyacrylamide gel electrophoresis for identifying fragmentation, ion exchange chromatography and isoelectric focusing for ...
Chullipalliyalil K +4 more
europepmc +3 more sources
Protein denaturation at the air-water interface and how to prevent it [PDF]
eLife, 2019 Electron cryo-microscopy analyzes the structure of proteins and protein complexes in vitrified solution. Proteins tend to adsorb to the air-water interface in unsupported films of aqueous solution, which can result in partial or complete denaturation. We
Edoardo D'Imprima +5 more
doaj +3 more sources
Detection of AGEs as markers for carbohydrate metabolism and protein denaturation. [PDF]
J Clin Biochem Nutr, 2014 Approximately 100 years have passed since the Maillard reaction was first reported in the field of food chemistry as a condensation reaction between reducing sugars and amino acids.
Nagai R +6 more
europepmc +4 more sources
Terahertz circular polarization sensing for protein denaturation based on a twisted dual-layer metasurface. [PDF]
Biomed Opt Express, 2022 Protein denaturation has very important research value in nutrition, biomedicine, and the food industry, which is caused by the changes in the molecular structure of the protein.
Zhang Z, Fan F, Shi W, Zhang T, Chang S.
europepmc +2 more sources
Free Radicals and ROS Induce Protein Denaturation by UV Photostability Assay. [PDF]
Int J Mol Sci, 2021 Oxidative stress, photo-oxidation, and photosensitizers are activated by UV irradiation and are affecting the photo-stability of proteins. Understanding the mechanisms that govern protein photo-stability is essential for its control enabling enhancement ...
Ruzza P +3 more
europepmc +2 more sources
The role of protein denaturation energetics and molecular chaperones in the aggregation and mistargeting of mutants causing primary hyperoxaluria type I. [PDF]
PLoS ONE, 2013 Primary hyperoxaluria type I (PH1) is a conformational disease which result in the loss of alanine:glyoxylate aminotransferase (AGT) function. The study of AGT has important implications for protein folding and trafficking because PH1 mutants may cause ...
Noel Mesa-Torres +6 more
doaj +4 more sources
Probing Protein Denaturation during Size-Exclusion Chromatography Using Native Mass Spectrometry. [PDF]
Anal Chem, 2020 Size-exclusion chromatography employing aqueous mobile phases with volatile salts at neutral pH combined with electrospray-ionization mass spectrometry (SEC-ESI-MS) is a useful tool to study proteins in their native state.
Ventouri IK +6 more
europepmc +2 more sources
Modalities of Protein Denaturation and Nature of Denaturants
International Journal of Pharmaceutical Sciences Review and Research, 2021 Denaturation of protein is a biological phenomenon in which a protein loses its native shape due to the breaking or disruption of weak chemical bonds and interactions which makes the protein biologically inactive. It is the process where properly folded proteins formed under physiological conditions is transformed to an unfolded protein under non ...
Vaishali V. Acharya, Pratima Chaudhuri
openaire +2 more sources