Results 51 to 60 of about 5,755,949 (365)

Analysis of the effects of thermal protein denaturation on the quality attributes of sous-vide cooked tuna

open access: yes, 2018
Traditional (low temperature, long time) and novel (low temperature, short time) sous-vide cooking of lean tuna were characterized by analyzing the effects of thermal protein denaturation (TPD) on quality attributes, such as color, appearance, shrinkage,
Yvan Llave   +5 more
semanticscholar   +1 more source

Calcium Binding and Disulfide Bonds Regulate the Stability of Secretagogin towards Thermal and Urea Denaturation. [PDF]

open access: yesPLoS ONE, 2016
Secretagogin is a calcium-sensor protein with six EF-hands. It is widely expressed in neurons and neuro-endocrine cells of a broad range of vertebrates including mammals, fishes and amphibia.
Kalyani Sanagavarapu   +4 more
doaj   +1 more source

A Monte Carlo simulation of a protein (CoVE) in a matrix of random barriers [PDF]

open access: yes, 2020
Monte Carlo simulations are performed to study structure and dynamics of a protein CoVE in random media generated by a random distribution of barriers at concentration c with a coarse-grained model in its native (low temperature) and denatured (high temperature) phase.
arxiv   +1 more source

Protein encapsulation via polyelectrolyte complex coacervation: Protection against protein denaturation.

open access: yesJournal of Chemical Physics, 2018
Complex coacervation can be used as a route to compartmentalize a variety of solutes such as organic small molecules, inorganic nanoparticles, and proteins within microscale coacervate droplets.
Mengmeng Zhao, N. Zacharia
semanticscholar   +1 more source

Microscopic mechanism for cold denaturation [PDF]

open access: yes, 2007
We elucidate the mechanism of cold denaturation through constant-pressure simulations for a model of hydrophobic molecules in an explicit solvent. We find that the temperature dependence of the hydrophobic effect is the driving force/induces/facilitates cold denaturation.
arxiv   +1 more source

Effect of heating strategies on whey protein denaturation--Revisited by liquid chromatography quadrupole time-of-flight mass spectrometry.

open access: yesJournal of Dairy Science, 2016
Previous standards in the area of effect of heat treatment processes on milk protein denaturation were based primarily on laboratory-scale analysis and determination of denaturation degrees by, for example, electrophoresis.
Marije Akkerman   +5 more
semanticscholar   +1 more source

Anti-tumour-promoting and thermal-induced protein denaturation inhibitory activities of β-sitosterol and lupeol isolated from Diospyros lotus L.

open access: yesNatural Product Research, 2016
In this study, the anti-tumour-promoting and thermal-induced protein denaturation inhibitory activities of β-sitosterol (1) and lupeol (2), isolated from Diospyros lotus L., were explored.
A. Rauf   +5 more
semanticscholar   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Visualization of early events in acetic acid denaturation of HIV-1 protease: a molecular dynamics study.

open access: yesPLoS ONE, 2011
Protein denaturation plays a crucial role in cellular processes. In this study, denaturation of HIV-1 Protease (PR) was investigated by all-atom MD simulations in explicit solvent.
Aditi Narendra Borkar   +3 more
doaj   +1 more source

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