Results 121 to 130 of about 42,092 (259)

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

Advanced Healthcare Materials, EarlyView.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano, M. Carmen Mera‐Delgado, Esther Moreno, Esther Larrea, Lecnia Aguirre, Jonathan Miguel Zanatta, Sónia Barros‐Carvalho, Iola F. Duarte, Ricardo Silvestre, Juan M. Irache, Javier Carrión, Socorro Espuelas   +11 more
wiley   +1 more source

Probiotic-driven modifications in structural properties enhance protein digestibility and amino acid availability in yogurt. [PDF]

Food Chem X
Yu C, Li S, Qin X, Liu J, Wang C, Huang Q, Sun E, Li Z, Shen Q, Shang N, Wang X.   +10 more
europepmc   +1 more source

Unraveling the digestion of milk protein [PDF]

The American Journal of Clinical Nutrition, 2013
R Paul, Ross, Gerald F, Fitzgerald, Catherine, Stanton   +2 more
openaire   +2 more sources

Temporal Immune and Metabolic Shifts Drive the Anti‐Tumor Efficacy of Resiquimod‐Loaded Nanoparticles in Peritoneal Carcinomatosis

Advanced Healthcare Materials, EarlyView.
Peritoneal carcinomatosis is a hard‐to‐treat spread of abdominal cancers that often returns after therapy. Nanoparticles were developed to retain an immune‐boosting drug in the abdomen. When combined with chemotherapy in mice, this approach eliminated tumors in many cases and prevented recurrence, helping the immune system mount a stronger, longer ...
Vanessa Chan, Po‐Han Chao, XuXin Sun, Jun Han, Sarah MacPherson, Lucas J. Andrew, Noah Y. Brittain, Tien Do, Marcel B. Bally, Julian J. Lum, Shyh‐Dar Li   +10 more
wiley   +1 more source

Age-dependent plant protein digestibility and implications for epitope generation and hormonal secretion. [PDF]

Curr Res Food Sci
Vivanco-Maroto SM, Zhang M, Gómez-Marín C, Santos-Hernández M, Miralles B, Recio I.   +5 more
europepmc   +1 more source

Engineering Nanoplatforms for Alzheimer's Disease Detection via Biomolecular Corona Proteomic and Lipidomic Profiling

Advanced Healthcare Materials, EarlyView.
Engineered nanoparticles capture disease‐specific biomolecular coronas that uncover hidden molecular features of Alzheimer's disease. Combined proteomic and lipidomic analyses reveal a characteristic shift in ribosomal machinery and energy metabolism, generating a multiomic fingerprint that supports accurate disease detection and opens new ...
Antonietta Greco, Roberto Baretta, Andrea Di Fonzo, Andrea Armirotti, Stefano Cinti, Mara Mirasoli, Marco Frasconi, Claudia Corbo   +7 more
wiley   +1 more source

Effects of dietary fibers varying in physicochemical properties on total endogenous protein losses and protein digestibility in broilers. [PDF]

Poult Sci
Habibi MF, Dorado-Montenegro S, García-Ruiz AI, Gerrits WJJ, Georgaki D, Kwakkel RP, de Vries S.   +6 more
europepmc   +1 more source

The degree of doneness affected molecular changes and protein digestibility of pork. [PDF]

Front Nutr, 2022
Han Y, Liu H, Li Q, Zhao D, Shan K, Ke W, Zhang M, Li C.   +7 more
europepmc   +1 more source

Bioprinting High‐Cell‐Density Cardiac Tissue Constructs With Sustained Contractile Function

Advanced Healthcare Materials, EarlyView.
Contractile cardiomyocytes in 3D culture provide insights into the behavior of the heart. Combining a 3D bioprinting approach with a multi‐electrode array allows the development of the 3D culture to be monitored over time, and matured cultures allow the effect of drugs on cardiac function to be modelled, replicating effects seen in clinical application.
Priscila Melo, Wing Tai Tung, Harvey Lewis, Kavin Hettiarachchilage, Babis Tzivelekis, Rolando Berlinguer‐Palmini, Ana Marina Ferreira, Jason Gill, Kenneth Dalgarno   +8 more
wiley   +1 more source

Ostrich-derived Bacillus safensis O-6 enhances broiler growth performance by modulating gut microbiota and protein digestibility. [PDF]

Poult Sci
Wang G, Chen Y, Xiao Y, Sun M, Li X, Akhtar M, You Y, Zhou X, Shi D.   +8 more
europepmc   +1 more source