Results 61 to 70 of about 42,092 (259)

Evaluation of undehydrated barley feed fractions and dried oat feed fractions from integrated starch-ethanol process in diets of growing pigs

Agricultural and Food Science, 1992
The nutrient digestibility and protein utilization of undehydrated barley fractions: protein (BP), protein fibre mixture (BPF) and distillers solids (DS) at two levels of inclusion in diets fortified to equal lysine content were assayed with growing pigs
Matti Näsi, Erkki Aimonen
doaj  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Comparison of Protein Digestibility of a Commercial Food Sample with a Sample of Home Made Food in Rats

Armaghane Danesh Bimonthly Journal, 2007
Introduction & Objective: Evaluation of the quality of food proteins have a great importance because of biological and economical impacts. Different biological, microbiological, chemical and combined methods have been used and introduced for determining
M Taghizade, Z Asemi
doaj  

Nutritional quality of the protein of Vigna unguiculata L. Walp and its protein isolate

Revista Ciência Agronômica
A protein's true digestibility and amino acid composition are important characteristics for its nutritional characterisation. This study determined the true digestibility of the protein from cowpea (Vigna unguiculata L. Walp.) and of its protein isolate,
Karoline de Macêdo Gonçalves Frota, Lays Arnaud Rosal Lopes, Izabel Cristina Veras Silva, José Alfredo Gomes Arêas   +3 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Effect of reduced crude protein diets on nutrient digestibility and feed efficiency in broiler chickens

Ukrainian Journal of Veterinary and Agricultural Sciences
The study aimed to evaluate the effect of reducing crude protein levels in diets on nutrient digestibility and feed efficiency in broiler chickens. The experiment was conducted on Cobb-500 broilers over a 42-day growing period.
M. Mandryha, M. Sychov
doaj   +1 more source

Penentuan Daya Cerna Protein In Vitro Ikan Bawal (Colossoma Macropomum) pada Umur Panen Berbeda

ComTech, 2014
Digestibility is part of the sample consumed and not released into the feces. This study discusses about the protein digestibility of tambaqui fish (Colossoma macropomum) at different ages and sizes in vitro. Protein digestibility is the ability of ...
Dede Saputra
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source