Results 121 to 130 of about 7,315 (215)

Meloidogyne graminicola protein disulfide isomerase may be a nematode effector and is involved in protection against oxidative damage

Scientific Reports, 2019
The rice root-knot nematode, Meloidogyne graminicola, is a serious pest in most rice-growing countries. Usually, nematodes employ antioxidants to counteract the harm of reactive oxygen species (ROS) and facilitate their infection.
Zhong-ling Tian, Ze-hua Wang, Munawar Maria, Nan Qu, Jing-wu Zheng   +4 more
doaj   +1 more source

Asparagine614 Determines the Transport and Function of the Murine Anti-Aging Protein Klotho

Cells
Klotho is an anti-aging protein whose deletion significantly reduces lifespan in mice, while its over-expression increases lifespan. Klotho is a type-I transmembrane protein that is N-glycosylated at eight positions within its ectodomain.
Zahra Fanaei-Kahrani, Christoph Kaether
doaj   +1 more source

Enzymatic dyeing of keratinous materials [PDF]

, 2003
Poster apresentado no "Biotrans Olomouc 2003 - 6th International Symposium on Biocatalysis and Biotransformations", em Olomouc, Czech Republic, 2003This study reports on the dyeing of keratinous materials using appropriate enzymatic systems – laccases ...
Paulo, Artur Cavaco, Prada, Enrique, Silva, Carla J. S. M., Tzanov, Tzanko, Zille, Andrea   +4 more
core  

Phenylhydrazone-based endoplasmic reticulum proteostasis regulator compounds with enhanced biological activity

eLife
Pharmacological enhancement of endoplasmic reticulum (ER) proteostasis is an attractive strategy to mitigate pathology linked to etiologically diverse protein misfolding diseases.
Gabriel M Kline, Lisa Boinon, Adrian Guerrero, Sergei Kutseikin, Gabrielle Cruz, Marnie P Williams, Ryan J Paxman, William E Balch, Jeffery W Kelly, Tingwei Mu, R Luke Wiseman   +10 more
doaj   +1 more source

\u3cem\u3eDrosophila\u3c/em\u3e Vitelline Membrane Assembly: A Critical Role for an Evolutionarily Conserved Cysteine in the “VM domain” of sV23 [PDF]

, 2010
The vitelline membrane (VM), the oocyte proximal layer of the Drosophila eggshell, contains four major proteins (VMPs) that possess a highly conserved “VM domain” which includes three precisely spaced, evolutionarily conserved, cysteines (CX7CX8C ...
Beauchamp, J. M., Manogaran, Anita L., Waring, Gail L., Wu, T.   +3 more
core   +1 more source

Protein disulfide isomerases are promising targets for predicting the survival and tumor progression in glioma patients. [PDF]

Aging (Albany NY), 2020
Peng Z, Chen Y, Cao H, Zou H, Wan X, Zeng W, Liu Y, Hu J, Zhang N, Xia Z, Liu Z, Cheng Q.   +11 more
europepmc   +1 more source

Snowy cotyledon 2: the identification of a zinc finger domain protein essential for chloroplast development in cotyledons but not in true leaves [PDF]

, 2018
In cotyledons of etiolated seedlings light-dependent transformation of etioplasts to chloroplasts marks the transition from heterotrophic to autotrophic growth.
Albrecht, Verónica, Apel, Klaus, Ingenfeld, Anke   +2 more
core  

Expression of protein disulfide isomerase A3Q481K variant associated with amyotrophic lateral sclerosis triggers disease features in mice

Neurobiology of Disease
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by loss of motoneurons and compromised proteostasis. Dysfunction of the endoplasmic reticulum (ER) has been identified as a transversal pathogenic mechanism associated
Martin Sepulveda, Francisca Martínez Traub, Patricia Ojeda, Viviana Perez, Jorge Ojeda, Jessica Mella, Rodrigo Diaz, Pablo Rozas, Matías Mansilla-Jaramillo, Amparo Zuleta, Guillermo Diaz, Bredford Kerr, Ute Woehlbier, Juan Pablo Henríquez, Danilo B. Medinas, Claudio Hetz   +15 more
doaj   +1 more source

Characterization of Giardia lamblia WB C6 clones resistant to nitazoxanide and to metronidazole [PDF]

, 2017
Objectives The characterization of Giardia lamblia WB C6 strains resistant to metronidazole and to the nitro-thiazole nitazoxanide [2-acetolyloxy-N-(5-nitro 2-thiazolyl) benzamide] as the parent compound of thiazolides, a novel class of anti-infective ...
Hemphill, Andrew, Müller, Joachim, Müller, Norbert, Sterk, Maaike   +3 more
core  

Selenium‐Centered Cascade Exchangers and Conformational Control Unlock Unique Patterns of Thiol‐Mediated Cellular Uptake

ChemistryEurope
Dynamic‐covalent electrophiles called cascade exchangers (CAXs) can reversibly engage cell‐surface thiols. Conjugates between CAXs and molecular or even protein‐sized cargos can deliver these cargos into cells by thiol‐mediated uptake (TMU); free CAXs ...
Filipe Coelho, Lukas Zeisel, Prof. Oliver Thorn‐Seshold, Prof. Stefan Matile   +3 more
doaj   +1 more source