Results 1 to 10 of about 43,163 (273)

Protein disulfide isomerase in cardiovascular disease [PDF]

Experimental and Molecular Medicine, 2020
Exploring enzymes’ influence on cardiovascular disease Efforts to untangle the functions of a large family of enzymes could lead researchers to new therapies for diverse cardiovascular diseases.
Bei Xiong, Vishwanath Jha, Jeong-Ki Min, Jaehyung Cho   +3 more
doaj   +4 more sources

Dual roles for a tick protein disulfide isomerase during the life cycle of the Lyme disease agent [PDF]

mBio
The protein disulfide isomerase (PDI) family is a group of enzymes that have thiol-disulfide oxidoreductase, disulfide isomerase, and redox-dependent chaperone activities.
Xiaotian Tang, Yingjun Cui, Ushuu Namarra, Xiuqi Tian, Freddie Rivas-Giorgi, Erol Fikrig   +5 more
doaj   +2 more sources

Protein disulfide isomerase A3 as novel biomarker for endometrial cancer [PDF]

Frontiers in Oncology, 2023
ObjectiveThis study aims to investigate the potential of PDIA3 as a novel prognostic biomarker and therapeutic target for Endometrial Cancer (EC) with the ultimate goal of improving survival rates in EC patients.MethodsThis study employed a combination ...
Fanrong Yu, Xin Liu, Min Li, Xiufen Liu, Xintai Wang, Xintai Wang, Meixiang Guo   +6 more
doaj   +2 more sources

Protein disulfide isomerase is essential for osteoblast differentiation in mice [PDF]

Communications Biology
Protein disulfide isomerase (PDI) is an oxidoreductase responsible for the formation, reduction and isomerization of disulfide bonds of nascent proteins in endoplasmic reticulum (ER).
Yue Lu, Aizhen Yang, Zhenzhen Zhao, Yue Han, Depei Wu, Yi Wu   +5 more
doaj   +2 more sources

Protein disulfide isomerase is essential for spermatogenesis in mice [PDF]

JCI Insight
Spermatogenesis requires precise posttranslational control in the endoplasmic reticulum (ER), but the mechanism remains largely unknown. The protein disulfide isomerase (PDI) family is a group of thiol oxidoreductases responsible for catalyzing the ...
Yaqiong Zhang, Aizhen Yang, Zhenzhen Zhao, Fengwu Chen, Xiaofeng Yan, Yue Han, Depei Wu, Yi Wu   +7 more
doaj   +2 more sources

Protein Disulfide Isomerase and Extracellular Adherence Protein Cooperatively Potentiate Staphylococcal Invasion into Endothelial Cells. [PDF]

Microbiol Spectr, 2023
Leidecker M, Bertling A, Hussain M, Bischoff M, Eble JA, Fender AC, Jurk K, Rumpf C, Herrmann M, Kehrel BE, Niemann S.   +10 more
europepmc   +2 more sources

Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204 [PDF]

Frontiers in Physiology
Redox processes can modulate vascular pathophysiology. The endoplasmic reticulum redox chaperone protein disulfide isomerase A1 (PDIA1) is overexpressed during vascular proliferative diseases, regulating thrombus formation, endoplasmic reticulum stress ...
Leonardo Y. Tanaka, Sandeep Kumar, Lucas F. Gutierre, Celso Magnun, Daniela Kajihara, Dong-Won Kang, Francisco R. M. Laurindo, Hanjoong Jo   +7 more
doaj   +2 more sources

A novel role for protein disulfide isomerase ERp18 in venous thrombosis. [PDF]

Thromb J
He C, Yang A, Zhang Y, Zhao Z, Lu Y, Zhang J, Wu Y.   +6 more
europepmc   +3 more sources

Tannic acid inhibits TNF-α signaling by targeting the protein disulfide isomerase and alleviates symptoms in an imiquimod-induced psoriasis mouse model. [PDF]

Cell Commun Signal
Jin W, Xia Y, Sun S, Tang H, Hu S, Zhang Y, Huang J, Liu P, Hu C, Guo J, Wang P, An P, Luo J, Wang L, Wang F, Luo Y, Zhu Y.   +16 more
europepmc   +2 more sources

Functions and mechanisms of protein disulfide isomerase family in cancer emergence. [PDF]

Cell Biosci, 2022
Rahman NSA, Zahari S, Syafruddin SE, Firdaus-Raih M, Low TY, Mohtar MA.   +5 more
europepmc   +3 more sources