Results 61 to 70 of about 1,414,042 (194)
Granzyme A Stimulates pDCs to Promote Adaptive Immunity via Induction of Type I IFN
Frontiers in Immunology, 2019 Granzyme A (GzmA), together with perforin, are well-known for their cytotoxic activity against tumor or virus-infected cells. In addition to this cytotoxic function, GzmA stimulates several immune cell types and induces inflammation in the absence of ...
Kanako Shimizu +10 more
doaj +1 more source
, 2017 We investigate dynamical coupling between water and amino acid side-chain residues in solvation dynamics by selecting residues often used as natural probes, namely tryptophan, tyrosine and histidine, located at different positions on protein surface and ...
Bagchi, Biman +2 more
core +1 more source
Dynamics of protein hydration water [PDF]
Physical Review E, 2015 We present the frequency- and temperature-dependent dielectric properties of lysozyme solutions in a broad concentration regime, measured at subzero temperatures and compare the results with measurements above the freezing point of water and on hydrated lysozyme powder.
Wolf, M. +4 more
openaire +4 more sources
eLifeThe neurotransmitter:sodium symporters (NSSs) are secondary active transporters that couple the reuptake of substrate to the symport of one or two sodium ions. One bound Na+ (Na1) contributes to the substrate binding, while the other Na+ (Na2) is thought
Solveig G Schmidt +3 more
doaj +1 more source
Dynamics of protein-protein encounter: a Langevin equation approach with reaction patches
, 2008 We study the formation of protein-protein encounter complexes with a Langevin equation approach that considers direct, steric and thermal forces.
Alberts B. +7 more
core +1 more source
Structural insights into tRNA recognition of the human FTSJ1-THADA complex
Communications BiologytRNA undergoes various post-transcriptional modifications in the anticodon loop. FTSJ1, a protein conserved among most eukaryotes, mediates 2’-O-methylations at position 32 (Nm32) or position 34 (Nm34), complexed with THADA or WDR6, respectively.
Kensuke Ishiguro +2 more
doaj +1 more source
, 2004 Current all-atom potential based molecular dynamics (MD) allow the identification of a protein's functional motions on a wide-range of time-scales, up to few tens of ns.
Carloni, Paolo +2 more
core +1 more source
Native geometry and the dynamics of protein folding
, 2004 In this paper we investigate the role of native geometry on the kinetics of protein folding based on simple lattice models and Monte Carlo simulations.
Abkevich +28 more
core +1 more source
Scientific ReportsAutism spectrum disorder (ASD) is a neurodevelopmental condition characterized by impairments in social interaction, challenges with communication, and repetitive behaviors.
Mikito Takahashi +5 more
doaj +1 more source
Quenching protein dynamics interferes with HIV capsid maturation
Nature Communications, 2017 The process of HIV particle maturation involves complex molecular transitions. Here the authors combine NMR spectroscopy, cryo-EM, and molecular dynamics simulations to provide insight into the conformational equilibria in CA-SP1 assemblies relevant to ...
Mingzhang Wang +16 more
doaj +1 more source