Results 101 to 110 of about 250,840 (309)
Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System
Advanced Functional Materials, EarlyView.A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim +4 more
wiley +1 more source
mBioMany gram-negative bacteria utilize a type III secretion system (T3SS) injectisome to translocate effector proteins directly into host cells. In Bordetella bronchiseptica, a respiratory pathogen of diverse mammals, the T3SS injectisome contains a unique ...
Ivana Malcova +3 more
doaj +1 more source
Role of the Srs2-Rad51 Interaction Domain in Crossover Control in Saccharomyces cerevisiae. [PDF]
, 2019 Saccharomyces cerevisiae Srs2, in addition to its well-documented antirecombination activity, has been proposed to play a role in promoting synthesis-dependent strand annealing (SDSA).
Ede, Christopher +8 more
core
Near‐Infrared Organic Photovoltaic Electrodes for Subretinal Neurostimulation
Advanced Functional Materials, EarlyView.Organic photovoltaic electrodes based on the D18:Y6 blend enable precise and light‐controlled activation of retinal ganglion cells in a degenerating retina. NIR Light‐driven activation of retinal ganglion cells, tunable stimulation parameters, and biocompatibility with human retinal organoids highlight their potential for next‐generation prosthetics ...
Andrea Corna +10 more
wiley +1 more source
Bacterial flagellar capping proteins adopt diverse oligomeric states
eLife, 2016 Flagella are crucial for bacterial motility and pathogenesis. The flagellar capping protein (FliD) regulates filament assembly by chaperoning and sorting flagellin (FliC) proteins after they traverse the hollow filament and exit the growing flagellum tip.
Sandra Postel +12 more
doaj +1 more source
Transforming growth factor-beta targets Formin-like 2 for Angiopoietin-like 4 secretion during the epithelial mesenchymal transition [PDF]
, 2019 Epithelial to Mesenchymal transition (EMT) is a highly dynamic process that plays a crucial role in tumor progression and metastasis. While remodelling of the actin cytoskeleton is a hallmark of EMT, the responsible actin regulating factors are less well
Moussi, Christel Jessica
core +1 more source
An All‐Optical Driven Bio‐Photovoltaic Interface for Active Control of Live Cells
Advanced Functional Materials, EarlyView.Bio‐photovoltaic Interface (BIO‐PV‐I) for live cell manipulation is presented. BIO‐PV‐I can be activated non‐invasively and remotely to control the spatial motility, adhesion, and morphology of cells adhering to it. BIO‐PV‐I uses a patterned light‐induced electric potential in iron‐doped lithium niobate crystals whose light‐driven and reversible nature,
Lisa Miccio +8 more
wiley +1 more source
Advanced Functional Materials, EarlyView.This study advances our understanding of aortic valve stenosis by capturing spatially resolved chemical and structural changes at the nanoscale. The findings highlight the potential of combined Raman and electron microscopy for understanding calcification mechanisms across diverse tissue types.
Robin H. M. Van der Meijden +11 more
wiley +1 more source
Stochastic calculus of protein filament formation under spatial confinement
New Journal of Physics, 2018 The growth of filamentous aggregates from precursor proteins is a process of central importance to both normal and aberrant biology, for instance as the driver of devastating human disorders such as Alzheimer's and Parkinson's diseases.
Thomas C T Michaels +2 more
doaj +1 more source
Molecular Basis for Environment Sensing by a Nucleoid-Structuring Bacterial Protein Filament. [PDF]
J Phys Chem Lett, 2021 Zhao X +4 more
europepmc +1 more source