Results 11 to 20 of about 257,652 (357)
Deimination, Intermediate Filaments and Associated Proteins [PDF]
International Journal of Molecular Sciences, 2020 Deimination (or citrullination) is a post-translational modification catalyzed by a calcium-dependent enzyme family of five peptidylarginine deiminases (PADs). Deimination is involved in physiological processes (cell differentiation, embryogenesis, innate and adaptive immunity, etc.) and in autoimmune diseases (rheumatoid arthritis, multiple sclerosis ...
Julie Briot +2 more
openalex +4 more sources
Collaborative protein filaments
The EMBO Journal, 2015 AbstractIt is now well established that prokaryotic cells assemble diverse proteins into dynamic cytoskeletal filaments that perform essential cellular functions. Although most of the filaments assemble on their own to form higher order structures, growing evidence suggests that there are a number of prokaryotic proteins that polymerise only in the ...
Debnath Ghosal, Jan Löwe
openalex +4 more sources
Filamentation activates bacterial Avs5 antiviral protein [PDF]
Nature CommunicationsBacterial antiviral STANDs (Avs) are evolutionarily related to the nucleotide-binding oligomerization domain (NOD)-like receptors widely distributed in immune systems across animals and plants. EfAvs5, a type 5 Avs from Escherichia fergusonii, contains an N-terminal SIR2 effector domain, a NOD, and a C-terminal sensor domain, conferring protection ...
Yiqun Wang +4 more
openalex +4 more sources
Sarcomere lattice geometry influences cooperative myosin binding in muscle. [PDF]
PLoS Computational Biology, 2007 In muscle, force emerges from myosin binding with actin (forming a cross-bridge). This actomyosin binding depends upon myofilament geometry, kinetics of thin-filament Ca(2+) activation, and kinetics of cross-bridge cycling.
Bertrand C W Tanner +2 more
doaj +1 more source
The Biological Role of Nestin(+)-Cells in Physiological and Pathological Cardiovascular Remodeling
Frontiers in Cell and Developmental Biology, 2018 The intermediate filament protein nestin was identified in diverse populations of cells implicated in cardiovascular remodeling. Cardiac resident neural progenitor/stem cells constitutively express nestin and following an ischemic insult migrate to the ...
Angelino Calderone, Angelino Calderone
doaj +1 more source
Nature Communications, 2021 The assembly of branched actin networks depends on the heterodimeric capping protein CP/CapZ. Combining cryoEM, in vitro reconstitution and cell biological assays, the authors show that CP not only prevents actin filament elongation but also selectively ...
Johanna Funk +5 more
doaj +1 more source
Cells, 2022 Desmin is the major intermediate filament protein of all three muscle cell types, and connects different cell organelles and multi-protein complexes such as the cardiac desmosomes. Several pathogenic mutations in the DES gene cause different skeletal and
Andreas Brodehl +3 more
doaj +1 more source
Structure of native glycolipoprotein filaments in honeybee royal jelly
Nature Communications, 2020 Female honeybee larvae develop into queens when they are fed exclusively with royal jelly (RJ) and major royal jelly protein 1 (MRJP1) is the main protein component of RJ. Here, the authors present the 3.5 Å cryo-EM structure of native RJ filament, where
Simone Mattei +5 more
doaj +1 more source
Intermediate Filament Protein Partnership in Astrocytes [PDF]
Journal of Biological Chemistry, 1999 Intermediate filaments are general constituents of the cytoskeleton. The function of these structures and the requirement for different types of intermediate filament proteins by individual cells are only partly understood. Here we have addressed the role of specific intermediate filament protein partnerships in the formation of intermediate filaments ...
C, Eliasson +7 more
openaire +2 more sources