Results 131 to 140 of about 259,716 (267)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Membrane Protein Folding and Biogenesis: Insights from Single-Molecule Force Spectroscopy. [PDF]

Chem Rev
Kim SA, Kim S, Nam J, Kim E, Yoon TY, Min D.   +5 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

QSyncFold: quantum neural network for multidimensional sync-discovery in protein folding. [PDF]

Brief Bioinform
Shi J, Du P, Zeng W, Wang W, Peng S, Li X.   +5 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Effect of Ergosterol on the Binding of KMP-11 with Phospholipid Membranes: Implications in Leishmaniasis

ACS Omega, 2019
Achinta Sannigrahi, Debasmita Mullick, Dwipanjan Sanyal, Sagnik Sen, Ujjwal Maulik, Krishnananda Chattopadhyay   +5 more
doaj   +1 more source

Catalyzing Protein Folding by Chaperones. [PDF]

Biology (Basel)
Huang Z, Horowitz S.
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

NAC promotes co-translational protein folding at the ribosomal tunnel exit. [PDF]

Mol Cell
Santos J, Günnigmann M, Gora RJ, Iljina M, Predin M, Kotan IE, De P, Choudhary D, Jang J, Tippmann F, Hins C, Ban N, Tans SJ, Shan SO, Kramer G, Bukau B.   +15 more
europepmc   +1 more source

Assisted Protein Folding [PDF]

Journal of Biological Chemistry, 1997
R W, Ruddon, E, Bedows
openaire   +2 more sources