Results 31 to 40 of about 11,494,730 (307)
Hybridization is a recurrent evolutionary stimulus in wild yeast speciation
Nature Communications, 2019 Hybridization can contribute to diversity from the genomic to the species level. Here, Eberlein, Hénault et al. investigate genomic, transcriptomic and phenotypic variation among wild lineages of the yeast Saccharomyces paradoxus and suggest that an ...
Chris Eberlein +7 more
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BMC Cancer, 2021 Background Icaritin, an active ingredient of the Chinese herb Epimedium, plays an anti-tumor role in liver cancer by inhibiting the proliferation of hepatocellular cells and promoting their apoptosis.
Hui Li +7 more
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Author Correction: Hybridization is a recurrent evolutionary stimulus in wild yeast speciation
Nature Communications, 2019 The original version of the Supplementary Information associated with this Article contained errors in Supplementary Figures 2, 12, 20 and 22. The HTML has been updated to include a corrected version of the Supplementary Information; the original ...
Chris Eberlein +7 more
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HBP1-mediated transcriptional repression of AFP inhibits hepatoma progression
Journal of Experimental & Clinical Cancer Research, 2021 Background Hepatoma is a common malignancy of the liver. The abnormal high expression of alpha-fetoprotein (AFP) is intimately associated with hepatoma progress, but the mechanism of transcriptional regulation and singularly activation of AFP gene in ...
Zhengyi Cao +7 more
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Oncogenesis, 2021 Golgi protein 73 (GP73) and alpha fetoprotein (AFP) serve as biomarkers for the diagnosis of hepatocellular carcinoma (HCC), and their serum levels correlate with patients’ outcomes. However, the mechanisms underlying these correlations are unknown. Here
Yujuan Liu +7 more
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Functions of the Prion Protein
, 2017 Although initially disregarded compared to prion pathogenesis, the functions exerted by the cellular prion protein PrPC have gained much interest over the past two decades. Research aiming at unraveling PrPC functions started to intensify when it became appreciated that it would give clues as to how it is subverted in the context of prion infection and,
Hirsch, Théo +2 more
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FLORA: a novel method to predict protein function from structure in diverse superfamilies [PDF]
, 2009 Predicting protein function from structure remains an active area of interest, particularly for the structural genomics initiatives where a substantial number of structures are initially solved with little or no functional characterisation.
Dallman Timothy J. +24 more
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Frontiers in Microbiology, 2019 Bacterial 3-oxoacyl-ACP reductase (OAR) catalyzes the 3-oxoacyl-ACP reduction step in the fatty acid synthesis pathway. At least 12 genes in the Pseudomonas aeruginosa genome are annotated as OAR-encoding genes.
Qiao-Qiao Guo +7 more
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Computational aspects of protein functionality [PDF]
Comparative and Functional Genomics, 2004 AbstractThe purpose of this short article is to examine certain aspects of protein functionality with relation to some key organizing ideas. This is important from a computational viewpoint in order to take account of modelling both biological systems and knowledge of these systems.
Paton, R. C., Toh, C.-H.
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Resistant Protein: Forms and Functions
Foods, 2022 Several global health risks are related to our dietary lifestyle. As a consequence of the overconsumption of ultra-processed and highly digestible protein (150–200% of the recommended value), excess dietary proteins reach the colon, are hydrolysed to peptides and amino acids by bacterial proteases and fermented to various potentially toxic end products.
Emanuele Zannini +2 more
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