Results 31 to 40 of about 521,366 (318)
Hsp90 Breaks the Deadlock of the Hsp70 Chaperone System [PDF]
, 2018 Protein folding in the cell requires ATP-driven chaperone machines such as the conserved Hsp70 and Hsp90. It is enigmatic how these machines fold proteins.
Mayer, Matthias +5 more
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BMC Cancer, 2021 Background Icaritin, an active ingredient of the Chinese herb Epimedium, plays an anti-tumor role in liver cancer by inhibiting the proliferation of hepatocellular cells and promoting their apoptosis.
Hui Li +7 more
doaj +1 more source
Hybridization is a recurrent evolutionary stimulus in wild yeast speciation
Nature Communications, 2019 Hybridization can contribute to diversity from the genomic to the species level. Here, Eberlein, Hénault et al. investigate genomic, transcriptomic and phenotypic variation among wild lineages of the yeast Saccharomyces paradoxus and suggest that an ...
Chris Eberlein +7 more
doaj +1 more source
Oncogenesis, 2021 Golgi protein 73 (GP73) and alpha fetoprotein (AFP) serve as biomarkers for the diagnosis of hepatocellular carcinoma (HCC), and their serum levels correlate with patients’ outcomes. However, the mechanisms underlying these correlations are unknown. Here
Yujuan Liu +7 more
doaj +1 more source
Virulence Functions of Autotransporter Proteins [PDF]
Infection and Immunity, 2001 Bacterial pathogens must execute a prodigious array of complex functions in order to survive, multiply, and disseminate within mammalian hosts. Virulence determinants are usually proteinaceous in nature and are often either secreted to the bacterial cell surface or released into the ...
Henderson, Ian R., Nataro, James P.
openaire +5 more sources
Author Correction: Hybridization is a recurrent evolutionary stimulus in wild yeast speciation
Nature Communications, 2019 The original version of the Supplementary Information associated with this Article contained errors in Supplementary Figures 2, 12, 20 and 22. The HTML has been updated to include a corrected version of the Supplementary Information; the original ...
Chris Eberlein +7 more
doaj +1 more source
Functions of the Prion Protein
, 2017 Although initially disregarded compared to prion pathogenesis, the functions exerted by the cellular prion protein PrPC have gained much interest over the past two decades. Research aiming at unraveling PrPC functions started to intensify when it became appreciated that it would give clues as to how it is subverted in the context of prion infection and,
Hirsch, Théo +2 more
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Resistant Protein: Forms and Functions
Foods, 2022 Several global health risks are related to our dietary lifestyle. As a consequence of the overconsumption of ultra-processed and highly digestible protein (150–200% of the recommended value), excess dietary proteins reach the colon, are hydrolysed to peptides and amino acids by bacterial proteases and fermented to various potentially toxic end products.
Emanuele Zannini +2 more
openaire +4 more sources
Inferring function using patterns of native disorder in proteins [PDF]
, 2007 Natively unstructured regions are a common feature of eukaryotic proteomes. Between 30% and 60% of proteins are predicted to contain long stretches of disordered residues, and not only have many of these regions been confirmed experimentally, but they ...
Swindells, MB +14 more
core +1 more source
An assessment of feature relevance in predicting protein function from sequence [PDF]
, 2004 Improving the performance of protein function prediction is the ultimate goal for a bioinformatician working in functional genomics. The classical prediction approach is to employ pairwise sequence alignments. However this method often faces difficulties
Tan, AC +17 more
core +1 more source