Results 41 to 50 of about 11,494,730 (307)

Virulence Functions of Autotransporter Proteins [PDF]

open access: yesInfection and Immunity, 2001
Bacterial pathogens must execute a prodigious array of complex functions in order to survive, multiply, and disseminate within mammalian hosts. Virulence determinants are usually proteinaceous in nature and are often either secreted to the bacterial cell surface or released into the ...
Henderson, Ian R., Nataro, James P.
openaire   +5 more sources

An empirical evaluation of the effectiveness of different types of predictor attributes in protein function prediction. [PDF]

open access: yes, 2009
Many classification schemes for defining protein functions, such as Gene Ontology (GO), are organised in a hierarchical structure. Nodes near the root of the hierarchy represent general functions while nodes near the leaves of the hierarchy represent ...
Segond, Marc   +11 more
core   +1 more source

Bioactivation and Regioselectivity of Pig Cytochrome P450 3A29 towards Aflatoxin B1

open access: yesToxins, 2016
Due to unavoidable contaminations in feedstuff, pigs are easily exposed to aflatoxin B1 (AFB1) and suffer from poisoning, thus the poisoned products potentially affect human health.
Jun Wu   +10 more
doaj   +1 more source

Identification and Enzyme Activity Comparison of Cellulase-producing Bacillus

open access: yesGuangdong nongye kexue, 2022
【Objective】The research was carried out to screen out celllulase-producing strains from 14 strains of bacteria in order to provide a material basis for the development of new feed additives.【Method】The cellulase-producing strains were screened out from ...
Xuebin JIANG   +4 more
doaj   +1 more source

Non-Contiguous Protein Recombination [PDF]

open access: yes, 2013
Swapping sequence elements among related proteins can produce chimeric proteins with novel behaviors and improved properties such as enhanced stability. Although homologous mutations are much more conservative than random mutations, chimeras of distantly-
Smith, Matthew Alexander
core   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi   +9 more
wiley   +1 more source

The FabA-FabB Pathway Is Not Essential for Unsaturated Fatty Acid Synthesis but Modulates Diffusible Signal Factor Synthesis in Xanthomonas campestris pv. campestris

open access: yesMolecular Plant-Microbe Interactions, 2023
Most bacteria use type II fatty acid synthesis (FAS) systems for synthesizing fatty acids, of which the conserved FabA-FabB pathway is considered to be crucial for unsaturated fatty acid (UFA) synthesis in gram-negative bacteria.
Yong-Hong Yu   +8 more
doaj   +1 more source

Hsp90 Breaks the Deadlock of the Hsp70 Chaperone System [PDF]

open access: yes, 2018
Protein folding in the cell requires ATP-driven chaperone machines such as the conserved Hsp70 and Hsp90. It is enigmatic how these machines fold proteins.
Mayer, Matthias   +5 more
core   +2 more sources

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

Subtype-Specific HIV-1 Protease and the Role of Hinge and Flap Dynamics in Drug Resistance: A Subtype C Narrative

open access: yesViruses
The HIV-1 aspartic protease is an effective target for the treatment of HIV/AIDS. Current therapy utilizes a selection of nine protease inhibitors (PIs) in combination with other classes of antiretroviral drugs.
Dean Sherry   +3 more
doaj   +1 more source

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