Results 41 to 50 of about 5,231,311 (300)
Frontiers in Microbiology, 2019 Bacterial 3-oxoacyl-ACP reductase (OAR) catalyzes the 3-oxoacyl-ACP reduction step in the fatty acid synthesis pathway. At least 12 genes in the Pseudomonas aeruginosa genome are annotated as OAR-encoding genes.
Qiao-Qiao Guo +7 more
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Identification and Enzyme Activity Comparison of Cellulase-producing Bacillus
Guangdong nongye kexue, 2022 【Objective】The research was carried out to screen out celllulase-producing strains from 14 strains of bacteria in order to provide a material basis for the development of new feed additives.【Method】The cellulase-producing strains were screened out from ...
Xuebin JIANG +4 more
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Conformational selection in protein binding and function
, 2014 Protein binding and function often involves conformational changes. Advanced NMR experiments indicate that these conformational changes can occur in the absence of ligand molecules (or with bound ligands), and that the ligands may 'select' protein ...
Paul, Fabian, Weikl, Thomas R.
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Protein‐Engineered Functional Materials
Advanced Healthcare Materials, 2019 AbstractProteins are versatile macromolecules that can perform a variety of functions. In the past three decades, they have been commonly used as building blocks to generate a range of biomaterials. Owing to their flexibility, proteins can either be used alone or in combination with other functional molecules. Advances in synthetic and chemical biology
Yao Wang +2 more
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Functional Evolution of Proteins [PDF]
Proteins: Structure, Function, and Bioinformatics, 2019 AbstractThe functional evolution of proteins advances through gene duplication followed by functional drift, whereas molecular evolution occurs through random mutational events. Over time, protein active‐site structures or functional epitopes remain highly conserved, which enables relationships to be inferred between distant orthologs or paralogs.
Jonathan Catazaro +3 more
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Bioactivation and Regioselectivity of Pig Cytochrome P450 3A29 towards Aflatoxin B1
Toxins, 2016 Due to unavoidable contaminations in feedstuff, pigs are easily exposed to aflatoxin B1 (AFB1) and suffer from poisoning, thus the poisoned products potentially affect human health.
Jun Wu +10 more
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Soy protein improves cardiovascular risk in subclinical hypothyroidism : a randomized double-blinded crossover study [PDF]
, 2017 © 2017 Endocrine Society. Background: Soy protein with isoflavones appears to have an adverse effect on thyroid function, but it is not known whether it is the protein or isoflavone component that is deleterious.
Atkin, Stephen L. +4 more
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Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano +7 more
wiley +1 more source
VirusesThe HIV-1 aspartic protease is an effective target for the treatment of HIV/AIDS. Current therapy utilizes a selection of nine protease inhibitors (PIs) in combination with other classes of antiretroviral drugs.
Dean Sherry +3 more
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Toxins, 2019 Human cytochrome P450 1A2 (CYP1A2) is one of the key CYPs that activate aflatoxin B1 (AFB1), a notorious mycotoxin, into carcinogenic exo-8,9-epoxides (AFBO) in the liver.
Jun Wu +7 more
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