Results 171 to 180 of about 648,804 (352)

Differential regulation of phosphorylation, structure, and stability of circadian clock protein FRQ isoforms [PDF]

, 2023
Xianyun Chen, Xiaolan Liu, Xihui Gan, Silin Li, Huan Ma, Lin Zhang, Peiliang Wang, Yunzhen Li, Tianyu Huang, Xiaolin Yang, Ling Fang, Yingying Liang, Jingjing Wu, Tongyue Chen, Zengxuan Zhou, Xiao Liu, Jinhu Guo   +16 more
openalex   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Long-read sequencing reveals the RNA isoform repertoire of neuropsychiatric risk genes in human brain

Genome Biology
Background Neuropsychiatric disorders are highly complex conditions and the risk of developing a disorder has been tied to hundreds of genomic variants that alter the expression and/or RNA isoforms made by risk genes.
Ricardo De Paoli-Iseppi, Shweta S. Joshi, Josie Gleeson, Yair D. J. Prawer, Yupei You, Ria Agarwal, Anran Li, Anthea Hull, Eloise M. Whitehead, Yoonji Seo, Rhea Kujawa, Raphael Chang, Mriga Dutt, Catriona McLean, Benjamin L. Parker, Michael B. Clark   +15 more
doaj   +1 more source

Molecular modelling of the HCMV IL-10 protein isoforms and analysis of their interaction with the human IL-10 receptor. [PDF]

PLoS One, 2022
Pantaleão SQ, Camillo LMB, Neves TC, Menezes IG, Stangherlin LM, Batista HBCR, Poole E, Nevels M, Philot EA, Scott AL, Carlan da Silva MC.   +10 more
europepmc   +1 more source

Identification of a Novel AMP-activated Protein Kinase β Subunit Isoform That Is Highly Expressed in Skeletal Muscle

, 1998
Claire Thornton, Michael Snowden, David Carling   +2 more
openalex   +1 more source

A novel PET probe to selectively image heat shock protein 90α/β isoforms in the brain [PDF]

, 2023
Takayuki Sakai, Hiroshi Ikenuma, Takashi Yamada, Saori Hattori, Aya Ogata, Junichiro Abe, Shinichi Imamura, Masanori Ichise, Mari Tada, Akiyoshi Kakita, Hiroko Koyama, Masaaki Suzuki, Takashi Kato, Kengo Ito, Yasuyuki Kimura   +14 more
openalex   +1 more source

Novel 3D‐Printed Biophotonic Scaffold Displaying Luminescence under Near‐Infrared Light for Photopharmacological Activation and Biological Signaling Compound Release

Advanced Healthcare Materials, EarlyView.
Despite significant efforts in developing novel biomaterials to regenerate tissue, only a few of them have successfully reached clinical use. It has become clear that the next generation of biomaterials must be multifunctional. Smart biomaterials can respond to environmental or external stimuli, interact in a spatial‐temporal manner, and trigger ...
Sonya Ghanavati, Ekin Opar, Virginia Alessandra Gobbo, Carlo Matera, Fabio Riefolo, Rossella Castagna, Julien Colombelli, Andrew Draganski, Joshua Baggott, Mika Lastusaari, Pau Gorostiza, Laeticia Petit, Jonathan Massera   +12 more
wiley   +1 more source

Expression of alternative transcription factor 4 mRNAs and protein isoforms in the developing and adult rodent and human tissues. [PDF]

Front Mol Neurosci, 2022
Sirp A, Shubina A, Tuvikene J, Tamberg L, Kiir CS, Kranich L, Timmusk T.   +6 more
europepmc   +1 more source

A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment

Advanced Healthcare Materials, EarlyView.
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim, Tianxin Cao, Zhengpeng Wan, Jaesang Kim, Zhuxuan Li, Legairre A. Radden II, Rakesh Santhanam, Eunkyung Clare Ko, Tatsuya Osaki, Sarah Spitz, Hyunmin Moon, Maria Proestaki, Seokbeom Roh, Gyudo Lee, Jessie S. Jeon, Curtis R. Warren, Roger D. Kamm   +16 more
wiley   +1 more source

Expression of p53 protein isoforms predicts survival in patients with multiple myeloma. [PDF]

Am J Hematol, 2022
Rojas EA, Corchete LA, De Ramón C, Krzeminski P, Quwaider D, García-Sanz R, Martínez-López J, Oriol A, Rosiñol L, Bladé J, Lahuerta JJ, San Miguel JF, González M, Mateos MV, Bourdon JC, Misiewicz-Krzeminska I, Gutiérrez NC.   +16 more
europepmc   +1 more source