Results 51 to 60 of about 441,552 (301)
Protein Binding to mRNA 3′ Isoforms
Current Protocols in Molecular Biology, 2019 AbstractHere we describe CLIP‐READS, a technique that combines elements of crosslinking and immunoprecipitation (CLIP) and 3′ region extraction and deep sequencing (READS), to provide a genome‐wide map of mRNA 3′ isoform binding by a given messenger ribonucleoprotein (mRNP). In CLIP‐READS, cells are grown to logarithmic phase and are irradiated with UV
Joseph V, Geisberg, Zarmik, Moqtaderi
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Acetylcholine receptor-aggregating activity of agrin isoforms and mapping of the active site. [PDF]
, 1995 Agrin is a basal lamina protein that induces aggregation of acetylcholine receptors (AChRs) and other molecules at the developing neuromuscular junction.
Ruegg, M. A. +8 more
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Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion [PDF]
, 2009 Two dynamin-related protein (DRP) families are essential for fusion of the outer and inner mitochondrial membranes, Fzo1 (yeast)/Mfn1/Mfn2 (mammals) and Mgm1 (yeast)/Opa1 (mammals), respectively.
Stahlberg, Henning +11 more
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Trafficking of the cellular isoform of the prion protein
Biomedicine & Pharmacotherapy, 1999 Transmissible spongiform encephalopathies form a group of fatal neurodegenerative disorders that have the unique property of being infectious, sporadic or genetic in origin. Although the nature of the responsible agent of these diseases is uncertain, it is clear that a protein called PrPSc has a central role in their pathology.
S, Lehmann, O, Milhavet, A, Mangé
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Diagnostic utility of prostate health index density prior to MRI-ultrasound fusion targeted biopsy
Exploration of Targeted Anti-tumor TherapyAim: Prostate biopsy can be prone to complications and thus should be avoided when unnecessary. Although the combination of magnetic resonance imaging (MRI), the prostate health index (PHI), and PHI density (PHID) has been shown to improve detection of ...
Benjamin H. Press +9 more
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Splice-Junction-Based Mapping of Alternative Isoforms in the Human Proteome
Cell Reports, 2019 Summary: The protein-level translational status and function of many alternative splicing events remain poorly understood. We use an RNA sequencing (RNA-seq)-guided proteomics method to identify protein alternative splicing isoforms in the human proteome
Edward Lau +6 more
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The Opposite Functions of CD30 Ligand Isoforms
Current Issues in Molecular BiologyTNFSF8/CD30 ligand is a TNF superfamily member expressed on several major immune cell types, including activated monocytes, B, and T cells. The signaling of CD30 ligand through its cognate CD30 receptor has been shown to have effects on cell ...
Ignat Printsev +2 more
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BMC Neurology, 2018 Background Post-translational modifications (PTMs) generate a tremendous protein diversity from the ~ 20,000 protein-coding genes of the human genome. In chronic pain conditions, exposure to pathological processes in the central nervous system could lead
Emmanuel Bäckryd +3 more
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The carbohydrates of the isoforms of three avian riboflavin‐binding proteins [PDF]
European Journal of Biochemistry, 1999 The carbohydrate chains of nine isoforms of chicken egg‐white riboflavin‐binding protein (RfBP) and six isoforms each of quail egg‐white and yolk RfBP have been structurally characterized. The two N‐glycosylation sites, Asn36 and Asn147, of the most abundant isoform of each of the three proteins were analyzed in further detail leading to the ...
A. Amoresano +5 more
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Dermatology Reports, 2010 14-3-3 is a highly conserved protein involved in a number of cellular processes including cell signalling, cell cycle regulation and gene transcription. Seven isoforms of the protein have been identified; β, γ, ε, ζ, η, σ and τ. The expression profile of
Line Raaby +4 more
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