Results 41 to 50 of about 441,552 (301)

Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus. [PDF]

, 2013
Nuclear myosin I (NM1) is a nuclear isoform of the well-known "cytoplasmic" Myosin 1c protein (Myo1c). Located on the 11(th) chromosome in mice, NM1 results from an alternative start of transcription of the Myo1c gene adding an extra 16 amino acids at ...
Dzijak, Rastislav, Eckhard Wolf, Oliver Eickelberg, Fuchs Helmut, Alexander Bohla, Schmidt, Volker, Rülicke, T., Hrabě de Angelis, M., Rohožková, Jana, Alžběta Kalendová, Martin Hrabě de Angelis, Schmidt Volker, Dzijak, R., Kalendová, Alžběta, Rathkolb, Birgit, Hozák, Pavel, Dzijak Rastislav, Hans, Wolfgang, Ali Önder Yildirim, Rathkolb, B., Venit, Tomáš, Wolf Eckhard, Hans Wolfgang, Yildirim Ali Önder, Fuchs, H., Hozák Pavel, Bohla Alexander, Stoeger Tobias, Gailus-Durner, Valérie, Jana Rohožková, Hrabé de Angelis, Martin, Kahle-Stephan, M., Valérie Gailus-Durner, Wolf, E., Stoeger, Tobias, Thomas Rülicke, Gailus-Durner, V., Volker Schmidt, Kahle Michal, Helmut Fuchs, Kahle, Michal, Eickelberg, O., Kalendova, A., Venit Tomáš, Eickelberg Oliver, Bohla, A., Rastislav Dzijak, Michal Kahle, Rohožková Jana, Yildirim, A.Ö., Venit, T., Eickelberg, Oliver, Stöger, T., Wolfgang Hans, Rülicke Thomas, Hans, W., Rohozkova, J., Rathkolb Birgit, Bohla, Alexander, Birgit Rathkolb, Rülicke, Thomas, Tobias Stoeger, Tomáš Venit, Fuchs, Helmut, de Angelis Martin Hrabě, Schmidt, V., Yildirim, Ali Önder, Gailus-Durner Valérie, Wolf, Eckhard, Hozak, P., Kalendová Alžběta, Pavel Hozák   +71 more
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Differential expression and MAL-dependent targeting of the L-MAG and S-MAG isoforms to myelin membranes [PDF]

, 2003
Many degenerative diseases of the nervous system, including Multiple Sclerosis and peripheral neuropathies, are triggered by an impaired interaction between the axons and their surrounding myelin sheaths.
Erb, Michael
core   +1 more source

Splice-mediated Variants of Proteins (SpliVaP) – data and characterization of changes in signatures among protein isoforms due to alternative splicing

BMC Genomics, 2008
Background It is often the case that mammalian genes are alternatively spliced; the resulting alternate transcripts often encode protein isoforms that differ in amino acid sequences. Changes among the protein isoforms can alter the cellular properties of
Thanaraj Thangavel, Orsini Massimiliano, Floris Matteo   +2 more
doaj   +1 more source

Mapping of tonoplast intrinsic proteins in maturing and germinating Arabidopsis seeds reveals dual localization of embryonic TIPs to the tonoplast and plasma membrane [PDF]

, 2011
We have mapped the expression of the tonoplast intrinsic protein (TIP) gene family members in Arabidopsis seeds by fluorescent protein tagging of their genomic sequences and confocal microscopy.
Mathias Sorieul, Stefano Gattolin, Gattolin, Stefano, Frigerio, Lorenzo, Sorieul, Mathias, Lorenzo Frigerio   +5 more
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In vivo imaging of the tonoplast intrinsic protein family in Arabidopsis roots [PDF]

, 2009
Background: Tonoplast intrinsic proteins (TIPs) are widely used as markers for vacuolar compartments in higher plants. Ten TIP isoforms are encoded by the Arabidopsis genome.
Sorieul Mathias, Frigerio Lorenzo, Gattolin Stefano, Gattolin, Stefano, Frigerio, Lorenzo, Khonsari Roman H, Hunter, P. R. (Paul R.), Sorieul, Mathias, Khonsari, Roman H., Hunter Paul R   +9 more
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Identification and classification of innexin gene transcripts in the central nervous system of the terrestrial slug Limax valentianus.

PLoS ONE, 2021
Intercellular gap junction channels and single-membrane channels have been reported to regulate electrical synapse and the brain function. Innexin is known as a gap junction-related protein in invertebrates and is involved in the formation of ...
Hisayo Sadamoto, Hironobu Takahashi, Suguru Kobayashi, Hirooki Kondoh, Hiroshi Tokumaru   +4 more
doaj   +1 more source

The Difference in Structural States between Canonical Proteins and Their Isoforms Established by Proteome-Wide Bioinformatics Analysis

Biomolecules, 2022
Alternative splicing is an important means of generating the protein diversity necessary for cellular functions. Hence, there is a growing interest in assessing the structural and functional impact of alternative protein isoforms. Typically, experimental
Zarifa Osmanli, Theo Falgarone, Turkan Samadova, Gudrun Aldrian, Jeremy Leclercq, Ilham Shahmuradov, Andrey V. Kajava   +6 more
doaj   +1 more source

Analysis of Intact Protein Isoforms by Mass Spectrometry [PDF]

Journal of Biological Chemistry, 2011
The diverse proteome of an organism arises from such events as single nucleotide substitutions at the DNA level, different RNA processing, and dynamic enzymatic post-translational modifications. This minireview focuses on the measurement of intact proteins to describe the diversity found in proteomes.
Jeremiah D, Tipton, John C, Tran, Adam D, Catherman, Dorothy R, Ahlf, Kenneth R, Durbin, Neil L, Kelleher   +5 more
openaire   +2 more sources

The Genetic Regulation of Alternative Splicing in Populus deltoides

Frontiers in Plant Science, 2020
Alternative splicing (AS) is a mechanism of regulation of the proteome via enabling the production of multiple mRNAs from a single gene. To date, the dynamics of AS and its effects on the protein sequences of individuals in a large and genetically ...
Jerald D. Noble, Kelly M. Balmant, Christopher Dervinis, Gustavo de los Campos, Gustavo de los Campos, Márcio F. R. Resende, Márcio F. R. Resende, Matias Kirst, Matias Kirst, Matias Kirst, William Brad Barbazuk, William Brad Barbazuk, William Brad Barbazuk, William Brad Barbazuk   +13 more
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Isoforms of contractile proteins

Progress in Biophysics and Molecular Biology, 1987
Although the mechanism of muscle contraction is essentially the same and the properties ofindividuai contractile proteins such as molecular mass and the overall structure are similar in different types of muscles, more subtle differences were found when muscles of different sources were investigated by using specific and sensitive biochemical ...
openaire   +2 more sources