Results 231 to 240 of about 115,342,253 (257)

Radiotherapy‐Induced Side Effects: Epidemiology, Pathogenesis, Prevention and Treatments

MedComm, Volume 7, Issue 10, October 2026.
Radiotherapy for malignancies frequently injures the organs’ systems through oxidative stress, fibrosis, inflammation, and vascular damage. This review systematically maps the epidemiology, pathogenesis, and emerging therapies to propose a mechanism‑network‑targeted framework for integrated, personalized care in radiation oncology.
Xiaowen Ma, Xiaoxuan Zhang, Pujun Zhao, Jiaxin Yang, Zhihao Li, Xiaoyang Han, Yixuan Wang, Zhenzhen Cui, Nian Liu, Min Li   +9 more
wiley   +1 more source

Immune‐Cell Dynamics in the Tumor Microenvironment: Implications for Cancer Therapy

MedComm, Volume 7, Issue 10, October 2026.
Immune‐cell dynamics in the tumor microenvironment converge on four major barriers to effective therapy: failed immune access, defective antigen visibility and priming, loss of effector maintenance, and suppressive tissue remodeling. These barriers emerge from local hypoxic, cytokine, metabolic, and stromal signals.
Pin Guo, Yizhao Xie, Rui Song, Mengdi Yang, Zhen Lin, Chao Guan, Zechen Wang, Jin Wen, Guang‐Liang Chen   +8 more
wiley   +1 more source

Expression of protein kinase A catalytic subunits in healthy and diseased mouse kidneys. [PDF]

Pflugers Arch
Fuchs S, Majer M, Ma Y, Harloff M, Taylor S, Schlossmann J.   +5 more
europepmc   +1 more source

Molecular mechanisms, pathogenesis and therapeutic advances of <i>Candida albicans</i> in oral candidiasis. [PDF]

Front Cell Infect Microbiol
Sahu BK, Debta P, Patra SK, Sahu MC, Mohanta TK, Panda SK.   +5 more
europepmc   +1 more source

Exploring the role of alpha-tocopherol in pain and inflammation: interplay with TRPV1, PKA, and PKC pathways. [PDF]

Korean J Pain
Jaffal S, Oran S.
europepmc   +1 more source

A PKA-selective inhibitor captures an open but more ordered conformation of the PKA catalytic subunit. [PDF]

Proc Natl Acad Sci U S A
Bruystens JGH, Wu J, Tan G, Bertinetti D, Zenn HM, Zimmermann B, Chen L, Köckenberger J, Massaro F, Sankaran B, Walters MS, Veglia G, Ferguson FM, Herberg FW, Taylor SS.   +14 more
europepmc   +1 more source

A Constellation of Fluorescent Biosensors to Illuminate the Galaxy of Protein Kinases. [PDF]

Chembiochem
Abbura T, Morris MC.
europepmc   +1 more source

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A Small Novel A-Kinase Anchoring Protein (AKAP) That Localizes Specifically Protein Kinase A-Regulatory Subunit I (PKA-RI) to the Plasma Membrane*

Journal of Biological Chemistry, 2012
Mark H Ellisman, Albert J.R. Heck, Marcel van der Heyden   +2 more
exaly