Results 251 to 260 of about 87,731 (343)

Sperm capacitation in bulls, rams, bucks, and boars: molecular mechanisms and species-specific differences. [PDF]

Front Vet Sci
Kaya A, Murray R, Bodu M, Hitit M, Memili E.   +4 more
europepmc   +1 more source

PDE4 Inhibition in Dermatologic Disease: Impacts Beyond Inflammation

International Journal of Dermatology, EarlyView.
This graphical abstract demonstrates the comprehensive mechanism of PDE4 inhibition in skin physiology. By increasing intracellular cAMP and activating PKA, PDE4 inhibitors exert pleiotropic effects, including immune modulation, pigmentation regulation, barrier enhancement, sensory neuron modulation, and improved wound healing with reduced fibrosis ...
Keana Khodadad, Nicole E. Chin, Raj Chovatiya   +2 more
wiley   +1 more source

High PGE₂ Levels Inhibit the Migration of Dendritic Cells by Modulating the PKA-CREB Axis Instead of Epac1-Rap1. [PDF]

Scientifica (Cairo)
Diao G, Huang J, Tian M, Li R, Guo J, Han J.   +5 more
europepmc   +1 more source

A Multifunctional β‐Defensin‐3 Mimetic Peptide Modulates Host–Biofilm Interactions and Reduces Bone Loss in Periodontitis

Journal of Periodontal Research, EarlyView.
BDMP, a peptide that can penetrate cells and tissues, offering antimicrobial and anti‐inflammatory effects, has been identified as a potential new therapy for periodontitis. ABSTRACT Aim This study evaluated the potential of a beta‐defensin‐3 mimetic peptide (BDMP), a synthetic cell‐penetrating peptide with antimicrobial and immunomodulatory properties,
Beom Soo Jo, Dong Woo Lee, Ji‐Young Lee, Sanghui Seok, Yu‐Bin Kim, Jue‐Yeon Lee, Shin‐Young Park, Young Dan Cho, Yang Jo Seol, Yoon Shin Park, Shahram Ghanaati, Homayoun H. Zadeh, Chong Pyung Chung, Yoon Jeong Park   +13 more
wiley   +1 more source

Levels of Protein CoAlation Regulate Redox Signaling Events of Human Sperm Capacitation. [PDF]

Antioxidants (Basel)
Onochie C, Filonenko V, Gout I, O'Flaherty C.   +3 more
europepmc   +1 more source

Characterization of the roles of phosholipase B1 and the cyclic-AMP (cAMP)-protein kinase A (PKA) pathway in nutritional and osmotic stress response in Schizosaccharomyces pombe

, 2012
Brittney McInnis, Marcus, Stevan, Busenlehner, Laura, Caldwell, Guy, Churchill, Perry, O'Donnell, Janis, University of Alabama. Dept. of Biological Sciences   +6 more
openalex   +1 more source

Intermittent hypoxia increases lipid insulin resistance in healthy humans: A randomized crossover trial

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
This scheme illustrates the main results of the present study showing an increase in circulating free fatty acids (FFA) that are likely to be related to several mechanisms like decrease in FFA insulin sensitivity and increase in FFA production. Significant changes are labelled in white, and non‐significant or hypothesis are labelled in pale green ...
Anne Briançon‐Marjollet, Marie Netchitaïlo, Fanny Fabre, Elise Belaidi, Claire Arnaud, Anne‐Laure Borel, Patrick Levy, Jean‐Louis Pépin, Renaud Tamisier   +8 more
wiley   +1 more source

<i>Baeckea frutescens</i> Suppresses Melanogenesis via Modulation of PKA/CREB and ERK/MAPK Pathways: Insights from Cellular, Zebrafish, and In Silico Analyses. [PDF]

Molecules
Yu CL, Huang YL, Huang Y, Zhong Y, Pang H, Wang GH.   +5 more
europepmc   +1 more source

Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all 10 PKA consensus phosphorylation sites

, 1993
Xiaowei Chang, J.A. Tabcharani, Yanming Hou, Thomas Jensen, Norbert Kartner, Noa Alon, John W. Hanrahan, J.R. Riordan   +7 more
openalex   +1 more source

Adenosine A2A Receptor Contributes to Bidirectional Remodeling of Microglial Inflammatory Responses During Methamphetamine Exposure. [PDF]

Int J Mol Sci
Hou Z, Zhang X, Yang G, Shen B, Dong W, Jing D, Hong S, Li L.   +7 more
europepmc   +1 more source