Calcium Stimulates Self-Assembly of Protein Kinase C α In Vitro. [PDF]
PLoS ONE, 2016 Protein kinase C α (PKCα) is a nodal regulator in several intracellular signaling networks. PKCα is composed of modular domains that interact with each other to dynamically regulate spatial-temporal function.
Carter J Swanson +6 more
doaj +1 more source
Mechanistic target of rapamycin (mTOR) signaling genes in decapod crustaceans: cloning and tissue expression of mTOR, Akt, Rheb, and S6 kinase in the green crab, Carcinus maenas, and blackback land crab, Gecarcinus lateralis [PDF]
, 2014 Mechanistic target of rapamycin (mTOR) controls global translation of mRNA into protein by phosphorylating p70 S6 kinase (S6K) and eIF4E-binding protein-1. Akt and Rheb, a GTP-binding protein, regulate mTOR protein kinase activity. Molting in crustaceans
Abuhagr, Ali M. +3 more
core +2 more sources
FEBS Letters, EarlyView.Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt +4 more
wiley +1 more source
PLoS ONE, 2020 Adenoviruses cause upper respiratory infections, conjunctivitis, keratitis, and gastrointestinal illness. These can be fatal in immunocompromised individuals.
Alice Liu +4 more
doaj +1 more source
Activation of cGMP-dependent Protein Kinase by Protein Kinase C [PDF]
Journal of Biological Chemistry, 2003 The cGMP-dependent protein kinases (PKG) are emerging as important components of mainstream signal transduction pathways. Nitric oxide-induced cGMP formation by stimulation of soluble guanylate cyclase is generally accepted as being the most widespread mechanism underlying PKG activation.
Nickolai O. Dulin +4 more
openaire +3 more sources
GABA\u3csub\u3eB\u3c/sub\u3e Receptors Couple to Gα\u3csub\u3eq\u3c/sub\u3e to Mediate Increases in Voltage-Dependent Calcium Current During Development [PDF]
, 2015 Metabotropic GABAB receptors are known to modulate the activity of voltage-dependent calcium channels. Previously, we have shown that GABAB receptors couple to a non-Gi/o G-protein to enhance calcium influx through L-type calcium channels by activating ...
Karls, Andrew S., Mynlieff, Michelle
core +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Effects of Newly Synthesized DCP-LA-Phospholipids on Protein Kinase C and Protein Phosphatases
Cellular Physiology and Biochemistry, 2013 Background/Aims: The linoleic acid derivative DCP-LA selectively activates PKCε and inhibits protein phosphatase 1 (PP1). In the present study, we have newly synthesized phosphatidyl-ethanolamine, -serine, -choline, and -inositol containing DCP-LA at the
Takeshi Kanno +5 more
doaj +1 more source
Inhibition of protein kinase C by resveratrol
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2003 Evidence is emerging that resveratrol (RV), a polyphenolic phytoaxelin present in dietary sources including red wine, may protect against atherosclerosis and cardiovascular disease by enhancing the integrity of the endothelium. In this study, the possibility that such beneficial effects of RV may arise from a modulation of protein kinase C (PKC ...
Anthony C. Cook +4 more
openaire +3 more sources
Phosphorylation by protein kinase C and the responsiveness of Mg2+-ATPase to Ca2+ of myofibrils isolated from stunned and non-stunned porcine myocardinm [PDF]
, 1997 Previously we showed in an in situ porcine model that the thiadiazinone derivative [+]EMD 60263, a Ca2+ sensitizer without phosphodiesterase III inhibitory properties, increased contractility more profoundly in stunned than in non-stunned myocardium ...
Bezstarosti, K. (Karel) +3 more
core +2 more sources