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Role of protein kinase R in metabolic homeostasis
2017Obesity related conditions, predominantly cardiovascular disease and diabetes constitute the most significant burden to healthcare in much of the western world. The physiological response to excess nutrients influences the health consequence of obesity. Hence regulation of cellular processes that maintain energy homeostasis, such as protein translation,
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Discovery and characterization of novel inhibitors of protein kinase R
2013Pelletier, Gerard (Internal/Supervisor)
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dlg–R proteins: modified guanylate kinases
Nature Genetics, 1992E V, Koonin, D F, Woods, P J, Bryant
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Unravelling the role of protein kinase R (PKR) in neurodegenerative disease: a review
Molecular Biology ReportsProtein Kinase R is an essential regulator of many cell activities and belongs to one of the largest and most functionally complex gene families. These are found all over the body, and by adding phosphate groups to the substrate proteins, they regulate their activity and coordinate the action of almost all cellular processes.
Maneesh Mohan +2 more
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Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules
Cell, 2021Trever Bivona +2 more
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Structural Framework for the Protein Kinase Family
Annual Review of Cell Biology, 1992Susan Taylor +2 more
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The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1
FASEB Journal, 1995Tony Hunter
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PRAK, a novel protein kinase regulated by the p38 MAP kinase
EMBO Journal, 1998Jiahuai Han, Yutaka Kato, Liguo New
exaly

