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Role of protein kinase R in metabolic homeostasis

2017
Obesity related conditions, predominantly cardiovascular disease and diabetes constitute the most significant burden to healthcare in much of the western world. The physiological response to excess nutrients influences the health consequence of obesity. Hence regulation of cellular processes that maintain energy homeostasis, such as protein translation,
openaire   +1 more source

dlg–R proteins: modified guanylate kinases

Nature Genetics, 1992
E V, Koonin, D F, Woods, P J, Bryant
openaire   +2 more sources

Unravelling the role of protein kinase R (PKR) in neurodegenerative disease: a review

Molecular Biology Reports
Protein Kinase R is an essential regulator of many cell activities and belongs to one of the largest and most functionally complex gene families. These are found all over the body, and by adding phosphate groups to the substrate proteins, they regulate their activity and coordinate the action of almost all cellular processes.
Maneesh Mohan   +2 more
openaire   +2 more sources

Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules

Cell, 2021
Trever Bivona   +2 more
exaly  

Structural Framework for the Protein Kinase Family

Annual Review of Cell Biology, 1992
Susan Taylor   +2 more
exaly  

Mitogen-activated protein kinase pathways

Current Opinion in Cell Biology, 1997
Melanie H Cobb
exaly  

PRAK, a novel protein kinase regulated by the p38 MAP kinase

EMBO Journal, 1998
Jiahuai Han, Yutaka Kato, Liguo New
exaly  

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