Results 91 to 100 of about 30,399 (190)
European Journal of Immunology, Volume 56, Issue 6, June 2026.Inducing memory inflation (MI) is a promising future vaccination strategy. We show that spread‐defective cytomegalovirus does not induce MI in the absence of CD4+ T cells. Support from CD4+ T cells can drive effector differentiation of MI cells, even late in the response, and contributes to long‐term response maintenance. ABSTRACT Memory inflation (MI)
Jack Barton +6 more
wiley +1 more source
Critical domains for NACC2-NTRK2 fusion protein activation.
PLoS ONENeurotrophic receptor tyrosine kinases (NTRKs) belong to the receptor tyrosine kinase (RTK) family. NTRKs are responsible for the activation of multiple downstream signaling pathways that regulate cell growth, proliferation, differentiation, and ...
Wei Yang +4 more
doaj +1 more source
iNew Medicine, Volume 2, Issue 2, June 2026.This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng +3 more
wiley +1 more source
Protein Science, Volume 35, Issue 6, June 2026.Abstract Surfactant protein D (SP‐D) plays a vital role in innate immunity by recognizing and binding to glycans on the surfaces of various pathogens. The oligomerization of SP‐D into dodecameric structures enhances its pathogen‐binding and antiviral activities.
Deng Li, Mona S. Minkara
wiley +1 more source
Nanobodies: A Promising Toolkit for Diagnostic Applications
SmartMat, Volume 7, Issue 3, June 2026.This review focuses on camelid‐derived nanobodies (VHHs) and explains how their small size and high stability support robust diagnostic design. Applications across ELISA, lateral flow assays, and PET/SPECT imaging are summarized, along with clinical progress such as caplacizumab.
Wei Wu +11 more
wiley +1 more source
Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk
Journal of Gastroenterology and Hepatology, Volume 41, Issue 6, Page 1722-1742, June 2026.ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin +2 more
wiley +1 more source
Journal of Neurochemistry, Volume 170, Issue 6, June 2026.Ischemic insult causes hyper‐glutamatergic signaling and neuronal death. The astrocytic transporter GLT‐1, which clears extracellular glutamate, is internalized and degraded in response to ischemia. We found that lysine‐directed post‐translational modifications (particularly ubiquitination) of the C‐terminal domain drive aberrant trafficking ...
Simran Kaur Gill +4 more
wiley +1 more source
Clathrin‐Mediated Endocytosis in Plants: Historical to Modern Advances
Traffic, Volume 27, Issue 2, June 2026.Ultrastructural studies by Bonnett and Newcomb in 1966 revealed the existence of coated vesicles budding from the plant cell plasma membrane. This review introduces this discovery and early questions regarding the biological significance of CME in plants highlighting advances in our understanding of the plant CME molecular machinery along with current ...
Timber Mattson +2 more
wiley +1 more source
Coronavirus nucleocapsid proteins assemble constitutively in high molecular oligomers
Scientific Reports, 2017 Coronaviruses (CoV) are enveloped viruses and rely on their nucleocapsid N protein to incorporate the positive-stranded genomic RNA into the virions. CoV N proteins form oligomers but the mechanism and relevance underlying their multimerization remain to
Yingying Cong +3 more
doaj +1 more source
Optical control over monomeric and multimeric protein hybrids [PDF]
, 2017 Living materials are based on proteins that adapt and change in structure and function continuously when in use; cellular microtubules, ATP synthases and ribosomes are but a few examples. Breathing life into semi-synthetic materials would allow improved understanding over protein regulation and dynamics, and how their integration into complex systems ...
openaire +2 more sources