Results 91 to 100 of about 3,377,935 (215)
Multimerization of tegument protein pp28 within the assembly compartment is required for cytoplasmic envelopment of human cytomegalovirus [PDF]
Human cytomegalovirus (HCMV) UL99-encoded pp28 is an essential tegument protein required for envelopment and production of infectious virus. Nonenveloped virions accumulate in the cytoplasm of cells infected with recombinant viruses with the UL99 gene ...
서준영, J.-Y. Seo, W. J. Britt
core +1 more source
Background The HIV-1 accessory protein known as viral infectivity factor or Vif binds to the host defence factor human APOBEC3G (hA3G) and prevents its assembly with viral particles and mediates its elimination through ubiquitination and degradation by ...
Presnyak Vlad +2 more
doaj +1 more source
Due to their remarkably high structural stability, proteins from extremophiles are particularly useful in numerous biological applications. Their utility as alternative protein scaffolds could be especially valuable in small antibody mimetic engineering.
Anna V Lomonosova +9 more
doaj +1 more source
Site‐specifically modified α‐synuclein containing DOPA or phosphorylation was prepared by ligation of a bacterially expressed N‐terminal polypeptide and a synthetic C‐terminal modified peptide. ABSTRACT α‐Synuclein (αSyn) is a major component of pathogenic Lewy bodies and Lewy neurites and is closely associated with Parkinson's disease.
Tatsuhito Matsuo +7 more
wiley +1 more source
Disulfide-Linked Head-to-Head Multimerization in the Mechanism of Ion Channel Clustering by PSD-95 [PDF]
The PSD-95/SAP90 family of PDZ-containing proteins is directly involved in the clustering of specific ion channels at synapses. We report that channel clustering depends on a conserved N-terminal domain of PSD-95 that mediates multimerization and ...
Hsueh, Yi-Ping +2 more
core +2 more sources
Background Boundaries in the Drosophila bithorax complex delimit autonomous regulatory domains that activate the parasegment (PS)-specific expression of homeotic genes.
Anna Fedotova +6 more
doaj +1 more source
Technologies for engineering repetitive DNA
Abstract Repetitive DNA, a fundamental architectural element of genomes, is widespread across organisms and comprises about 54% of the human genome. With advances in long‐read sequencing and bioinformatics approaches, highly repetitive sequences can now be characterized in depth.
Shuting Ma, Yali Cui, Yi Wu
wiley +1 more source
Multimerization of peptide antigens for production of stable immunogens in transgenic plants
Previous literature addressing the production of recombinant proteins in heterologous systems has consistently shown that proteins capable of forming complex structures tend to accumulate within host cells at relatively higher levels than monomeric forms.
Reytor, Edel +3 more
core +1 more source
Antigenic Properties of N Protein of Hantavirus
Hantavirus causes two important rodent-borne viral zoonoses, hemorrhagic fever with renal syndrome (HFRS) in Eurasia and hantavirus pulmonary syndrome (HPS) in North and South America.
Kumiko Yoshimatsu, Jiro Arikawa
doaj +1 more source
Is HIV-1 Gag and Gag-Pol multimerization initiated during protein translation?
Is HIV-1 Gag and Gag-Pol multimerization initiated during protein ...
S Crowe (13428231) +4 more
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