Results 91 to 100 of about 3,377,935 (215)

Multimerization of tegument protein pp28 within the assembly compartment is required for cytoplasmic envelopment of human cytomegalovirus [PDF]

open access: yes, 2008
Human cytomegalovirus (HCMV) UL99-encoded pp28 is an essential tegument protein required for envelopment and production of infectious virus. Nonenveloped virions accumulate in the cytoplasm of cells infected with recombinant viruses with the UL99 gene ...
서준영, J.-Y. Seo, W. J. Britt
core   +1 more source

The dimerization domain of HIV-1 viral infectivity factor Vif is required to block virion incorporation of APOBEC3G

open access: yesRetrovirology, 2007
Background The HIV-1 accessory protein known as viral infectivity factor or Vif binds to the host defence factor human APOBEC3G (hA3G) and prevents its assembly with viral particles and mediates its elimination through ubiquitination and degradation by ...
Presnyak Vlad   +2 more
doaj   +1 more source

Extremophilic 50S Ribosomal RNA-Binding Protein L35Ae as a Basis for Engineering of an Alternative Protein Scaffold.

open access: yesPLoS ONE, 2015
Due to their remarkably high structural stability, proteins from extremophiles are particularly useful in numerous biological applications. Their utility as alternative protein scaffolds could be especially valuable in small antibody mimetic engineering.
Anna V Lomonosova   +9 more
doaj   +1 more source

No Significant Secondary Structural Change of α‐Synuclein Monomer by Site‐Specific DOPA or Phosphorylation Introduction in Its C‐Terminal Region

open access: yesJournal of Peptide Science, Volume 32, Issue 9, September 2026.
Site‐specifically modified α‐synuclein containing DOPA or phosphorylation was prepared by ligation of a bacterially expressed N‐terminal polypeptide and a synthetic C‐terminal modified peptide. ABSTRACT α‐Synuclein (αSyn) is a major component of pathogenic Lewy bodies and Lewy neurites and is closely associated with Parkinson's disease.
Tatsuhito Matsuo   +7 more
wiley   +1 more source

Disulfide-Linked Head-to-Head Multimerization in the Mechanism of Ion Channel Clustering by PSD-95 [PDF]

open access: yes, 1997
The PSD-95/SAP90 family of PDZ-containing proteins is directly involved in the clustering of specific ion channels at synapses. We report that channel clustering depends on a conserved N-terminal domain of PSD-95 that mediates multimerization and ...
Hsueh, Yi-Ping   +2 more
core   +2 more sources

Functional dissection of the developmentally restricted BEN domain chromatin boundary factor Insensitive

open access: yesEpigenetics & Chromatin, 2019
Background Boundaries in the Drosophila bithorax complex delimit autonomous regulatory domains that activate the parasegment (PS)-specific expression of homeotic genes.
Anna Fedotova   +6 more
doaj   +1 more source

Technologies for engineering repetitive DNA

open access: yesQuantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Repetitive DNA, a fundamental architectural element of genomes, is widespread across organisms and comprises about 54% of the human genome. With advances in long‐read sequencing and bioinformatics approaches, highly repetitive sequences can now be characterized in depth.
Shuting Ma, Yali Cui, Yi Wu
wiley   +1 more source

Multimerization of peptide antigens for production of stable immunogens in transgenic plants

open access: yes, 2007
Previous literature addressing the production of recombinant proteins in heterologous systems has consistently shown that proteins capable of forming complex structures tend to accumulate within host cells at relatively higher levels than monomeric forms.
Reytor, Edel   +3 more
core   +1 more source

Antigenic Properties of N Protein of Hantavirus

open access: yesViruses, 2014
Hantavirus causes two important rodent-borne viral zoonoses, hemorrhagic fever with renal syndrome (HFRS) in Eurasia and hantavirus pulmonary syndrome (HPS) in North and South America.
Kumiko Yoshimatsu, Jiro Arikawa
doaj   +1 more source

Is HIV-1 Gag and Gag-Pol multimerization initiated during protein translation?

open access: yes, 2000
Is HIV-1 Gag and Gag-Pol multimerization initiated during protein ...
S Crowe (13428231)   +4 more
core  

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