Results 11 to 20 of about 30,129 (222)

mRNA and DNA selection via protein multimerization: YB-1 as a case study. [PDF]

Nucleic Acids Res, 2015
Kretov DA, Curmi PA, Hamon L, Abrakhi S, Desforges B, Ovchinnikov LP, Pastré D.   +6 more
europepmc   +3 more sources

Interactions Between Hantavirus Nucleoprotein and Glycoproteins: A Quantitative Fluorescence Microscopy Study [PDF]

Viruses
Orthohantaviruses are tri-segmented negative-sense RNA viruses that can cause severe pathologies in humans. Currently, limited information exists on the molecular interactions driving orthohantavirus assembly in infected cells.
Amit Koikkarah Aji, Titas Mandal, Salvatore Chiantia   +2 more
doaj   +2 more sources

Multimerized epitope tags for high-sensitivity protein detection [PDF]

G3: Genes, Genomes, Genetics
Abstract A detailed understanding of the function of a gene requires knowledge of the cellular and subcellular distribution of its encoded protein(s). For proteins expressed at low levels, antibodies that recognize single epitopes may not be sufficient for visualizing expression.
R Steven Stowers
openalex   +3 more sources

The Predicted Structure of S. cerevisiae Ssp1 Reveals Parallel Evolution in the Pil1 BAR Domain Family Proteins of Ascomycetes [PDF]

Journal of Fungi
BAR domains are a superfamily of widely conserved membrane binding motifs. In fungi, Pil1 family proteins are BAR domain containing proteins involved in organizing the plasma membrane. S.
Yasuyuki Suda, Aaron M. Neiman
doaj   +2 more sources

The A128T resistance mutation reveals aberrant protein multimerization as the primary mechanism of action of allosteric HIV-1 integrase inhibitors. [PDF]

J Biol Chem, 2013
Feng L, Sharma A, Slaughter A, Jena N, Koh Y, Shkriabai N, Larue RC, Patel PA, Mitsuya H, Kessl JJ, Engelman A, Fuchs JR, Kvaratskhelia M.   +12 more
europepmc   +3 more sources

Free mRNA in excess upon polysome dissociation is a scaffold for protein multimerization to form stress granules. [PDF]

Nucleic Acids Res, 2014
Bounedjah O, Desforges B, Wu TD, Pioche-Durieu C, Marco S, Hamon L, Curmi PA, Guerquin-Kern JL, Piétrement O, Pastré D.   +9 more
europepmc   +3 more sources

Allosteric HIV-1 integrase inhibitors promote aberrant protein multimerization by directly mediating inter-subunit interactions: Structural and thermodynamic modeling studies. [PDF]

Protein Sci, 2016
Deng N, Hoyte A, Mansour YE, Mohamed MS, Fuchs JR, Engelman AN, Kvaratskhelia M, Levy R.   +7 more
europepmc   +3 more sources

Vac14 protein multimerization is a prerequisite step for Fab1 protein complex assembly and function. [PDF]

J Biol Chem, 2013
Alghamdi TA, Ho CY, Mrakovic A, Taylor D, Mao D, Botelho RJ.   +5 more
europepmc   +3 more sources

TauLUM, an in vivo Drosophila sensor of tau multimerization, identifies neuroprotective interventions in tauopathy

Cell Reports: Methods, 2022
Summary: Tau protein aggregates are a defining neuropathological feature of “tauopathies,” a group of neurodegenerative disorders that include Alzheimer’s disease.
Simon A. Levy, Gabrielle Zuniga, Elias M. Gonzalez, David Butler, Sally Temple, Bess Frost   +5 more
doaj   +1 more source

Tandem Multimerization Can Enhance the Structural Homogeneity and Antifungal Activity of the Silkworm Protease Inhibitor BmSPI39

Cells, 2023
Previous studies have shown that BmSPI39, a serine protease inhibitor of silkworm, can inhibit virulence-related proteases and the conidial germination of insect pathogenic fungi, thereby enhancing the antifungal capacity of Bombyx mori.
Youshan Li, Yuan Wang, Rui Zhu, Xi Yang, Meng Wei, Zhaofeng Zhang, Changqing Chen, Ping Zhao   +7 more
doaj   +1 more source