Results 51 to 60 of about 992,662 (310)

SAMHD1 Phosphorylation at T592 Regulates Cellular Localization and S-phase Progression

Frontiers in Molecular Biosciences, 2021
SAMHD1 activity is regulated by a network of mechanisms including phosphorylation, oxidation, oligomerization, and others. Significant questions remain about the effects of phosphorylation on SAMHD1 function and activity. We investigated the effects of a
Stephanie Batalis, LeAnn C. Rogers, Wayne O. Hemphill, Christopher H. Mauney, David A. Ornelles, Thomas Hollis   +5 more
doaj   +1 more source

Whey proteins interact with lipids during autoxidation primarly via the production of reactive carbonyl species [PDF]

, 2010
Nowadays, it is well recognized that polyunsaturated fatty acids (PUFAs) can provide extensive nutritional and health benefits. Thus, ω-3 PUFAs have been considered to contribute to the prevention of several diseases.
Cucu, Tatiana, De Meulenaer, Bruno, Devreese, Bart, Kerkaert, Barbara, Mestdagh, Frédéric   +4 more
core   +1 more source

Effects of organic plant oils and role of oxidation on nutrient utilization in juvenile rainbow trout (Oncorhynchus mykiss) [PDF]

, 2012
The study compared the effect of four either fresh or force oxidized organic plant oils in diets for juvenile rainbow trout (Oncorhynchus mykiss) in which 47% of conventional LT fish meal protein was substituted by a mixture of 3 organic plant protein ...
A. Jokumsen, Bell, Bligh, Bransden, Børsting, C. Jacobsen, Caballero, Dalsgaard, Fountoulaki, Geurden, Geurden, I. Lund, J. Dalsgaard, J. Holm, J.H. Hansen, Jobling, Kaitaranta, Kasumyan, Kolar, Koshio, Laohabanjong, Lund, Lund, Lutterodt, Menoyo, Mente, Ng, Peng, Petersen, Petterson, Pickova, Ping, Shahidi, Shantha, Singh, Sun-Waterhouse, Takeda, Tyl   +37 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The Eye Lens Protein, γS Crystallin, Undergoes Glutathionylation-Induced Disulfide Bonding Between Cysteines 22 and 26

Biomolecules
The oxidation of cysteines in crystallins is a major age-related modification associated with cataract formation. The purpose of this research was to determine the susceptibility of γS-crystallin to glutathionylation-induced oxidation and disulfide bond ...
Kate Halverson-Kolkind, David C. Thorn, Martin Tovar-Ramirez, Eugene Shakhnovich, Larry David, Kirsten Lampi   +5 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Impact of Dehydration Processing on Scallop (Patinopecten yessoensis) Adductor Muscle: Structural and Oxidative Insights

Foods
This study investigated the impact of four drying techniques—hot air drying (HAD), vacuum hot air drying (VFAD), microwave drying (MWD), and vacuum freeze-drying (VFD)—on the structural, physicochemical, and functional properties of scallop adductor ...
Huaqiong Li, Yulong Zhao, Jian Shi, Manat Chaijan, Xichang Wang, Mingyu Yin   +5 more
doaj   +1 more source

Development of assays for biomarkers of oxidative damage to assess the efficacy of fruit-derived antioxidants : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]

, 2003
The diet is a very important part of maintaining a healthy lifestyle. Increased consumption of fruits and vegetables is one practice postulated to decrease the incidence of diseases such as cancer, cardiovascular disease and other disorders.
Barnett, Laura Evelyn
core  

Protein oxidation in Huntington disease [PDF]

BioFactors, 2012
AbstractHuntington disease (HD) is an inherited neurodegenerative disorder caused by expansion of CAG repeats in the huntingtin gene, affecting initially the striatum and progressively the cortex. Oxidative stress, and consequent protein oxidation, has been described as important to disease progression.
Sorolla Bardají, Maria Alba, Rodríguez Colman, Maria José, Vall-llaura Espinosa, Núria, Tamarit Sumalla, Jordi, Ros Salvador, Joaquim, Cabiscol Català, Elisa   +5 more
openaire   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source