Results 81 to 90 of about 992,662 (310)
Medicines, 2018 Background: Ascorbate is often applied to enhance stability and robustness of brine-injected pork chops sold for retail, but may affect protein oxidation, while plant extracts are potential substitutes. Methods: Brine-injected pork chops (weight-gain ~12%
Sisse Jongberg +2 more
doaj +1 more source
Unexpected transformation of dissolved phenols to toxic dicarbonyls by hydroxyl radicals and UV light. [PDF]
, 2018 Water treatment systems frequently use strong oxidants or UV light to degrade chemicals that pose human health risks. Unfortunately, these treatments can result in the unintended transformation of organic contaminants into toxic products.
Ford, Breanna +3 more
core +1 more source
Oxidative Stress and Sarcomeric Proteins [PDF]
Circulation Research, 2013 Oxidative stress accompanies a wide spectrum of clinically important cardiac disorders, including ischemia/reperfusion, diabetes mellitus, and hypertensive heart disease. Although reactive oxygen species (ROS) can activate signaling pathways that contribute to ischemic preconditioning and cardioprotection, high levels of ROS induce structural ...
openaire +2 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Shipin gongye ke-jiThis study aimed to investigate the effects of high-pressure processing (HPP) and ultrasound treatment on the microstructure, protein oxidation, and digestibility of Procambarus clarkii.
Zhihui WANG +8 more
doaj +1 more source
Cell signaling promoting protein carbonylation does not cause sulfhydryl oxidation: implications to the mechanism of redox signaling [PDF]
, 2017 Reactive oxygen species (ROS) have been recognized as second messengers, however, targeting mechanisms for ROS in cell signaling have not been defined.
Almansour, Faisal +4 more
core +3 more sources
Oxidative protein folding in bacteria [PDF]
Molecular Microbiology, 2002 SummaryTen years ago it was thought that disulphide bond formation in prokaryotes occurred spontaneously. Now two pathways involved in disulphide bond formation have been well characterized, the oxidative pathway, which is responsible for the formation of disulphides, and the isomerization pathway, which shuffles incorrectly formed disulphides ...
Collet, Jean-Francois +1 more
openaire +3 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Shipin gongye ke-jiTo address the quality deterioration of porcine liver during frozen storage, the impacts of different freezing methods on porcine liver were investigated, including −20 ℃ conventional air freezing (CAF), −80 ℃ refrigerator cryogenic freezing (RCF) and ...
Ge ZHANG, Juan YOU, Hong YANG
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source