Results 11 to 20 of about 2,399,730 (304)
Classification of an eIF‐2 phosphatase as a type‐2 protein phosphatase [PDF]
FEBS Letters, 1980 A. Stewart +3 more
semanticscholar +3 more sources
PPP2R1A (protein phosphatase 2 regulatory subunit A, alpha) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2018 Review on PPP2R1A, with data on DNA, on the protein encoded, and where the gene is implicated.
Razia Sultana +3 more
semanticscholar +3 more sources
Modulation of VEGF receptor 2 signaling by protein phosphatases [PDF]
Pharmacological Research, 2017 Phosphorylation of serines, threonines, and tyrosines is a central event in signal transduction cascades in eukaryotic cells. The phosphorylation state of any particular protein reflects a balance of activity between kinases and phosphatases. Kinase biology has been exhaustively studied and is reasonably well understood, however, much less is known ...
Federico, Corti, Michael, Simons
openaire +2 more sources
Bcl-2 Targets Protein Phosphatase 1α to Bad [PDF]
The Journal of Immunology, 2001 Abstract The diverse forms of protein phosphatase 1 (PP1) in vivo result from the association of the catalytic subunit with different regulatory subunits. We recently have described that PP1α is a Ras-activated Bad phosphatase that regulates IL-2 deprivation-induced apoptosis.
Ayllón, Verónica +7 more
openaire +4 more sources
Polycystin-1 is required for insulin-like growth factor 1-induced cardiomyocyte hypertrophy.
PLoS ONE, 2021 Cardiac hypertrophy is the result of responses to various physiological or pathological stimuli. Recently, we showed that polycystin-1 participates in cardiomyocyte hypertrophy elicited by pressure overload and mechanical stress.
Carolina Fernández +10 more
doaj +1 more source
PTK2 and PTPN11 expression in myelodysplastic syndromes
Clinics, 2013 OBJECTIVE: The aim of this study was to evaluate the expression of protein tyrosine kinase 2 and protein tyrosine phosphatase non-receptor type 11, which respectively encode focal adhesion kinase protein and src homology 2 domain-containing protein ...
Mariana Lazarini +6 more
doaj +1 more source
Scaffold Role of DUSP22 in ASK1-MKK7-JNK Signaling Pathway. [PDF]
PLoS ONE, 2016 Mitogen-activated protein kinases (MAPKs) are involved in a variety of intracellular events such as gene expression, cell proliferation, and programmed cell death.
Anna Ju +8 more
doaj +1 more source
Molecules, 2023 Src homology 2 domain-containing protein tyrosine phosphatase 1 (SHP1), a non-receptor member of the protein tyrosine phosphatase (PTP) family, negatively regulates several signaling pathways that are responsible for pathological cell processes in ...
Huiqing Chen +7 more
doaj +1 more source
PLoS Genetics, 2016 The phytohormone abscisic acid (ABA) regulates plant growth, development and responses to biotic and abiotic stresses. The core ABA signaling pathway consists of three major components: ABA receptor (PYR1/PYLs), type 2C Protein Phosphatase (PP2C) and ...
Yueh-Ju Hou +13 more
doaj +1 more source
Molecules, 2021 Natural products have continued to offer tremendous opportunities for drug development, as they have long been used in traditional medicinal systems. SHP2 has served as an anticancer target.
Se Jeong Kwon +4 more
doaj +1 more source