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How phosphorylation activates the protein phosphatase-1 • inhibitor-2 complex

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2013
Phosphorylation regulates activity of many proteins; however, atomic level details are known for very few examples. Inhibitor-2 (I2) squelches the ubiquitous protein phosphatase-1 (PP1) enzyme activity by blocking access to the metal-containing active site.
openaire   +2 more sources

PPP2R5A: A multirole protein phosphatase subunit in regulating cancer development.

Cancer Letters, 2018
Z.Q. Mao   +4 more
semanticscholar   +1 more source

Protein phosphatase inhibitor-2

AfCS-Nature Molecule Pages, 2006
openaire   +1 more source

PTEN Dual Lipid- and Protein-Phosphatase Function in Tumor Progression

Cancers, 2022
Glenn Merlino, Yanlin Yu, Yu Yanlin
exaly  

Pancreatic tumor cells with mutant K-ras suppress ERK activity by MEK-dependent induction of MAP kinase phosphatase-2.

Biochemical and Biophysical Research Communications - BBRC, 2001
M. Yip-Schneider   +2 more
semanticscholar   +1 more source

Molecular basis for TPR domain-mediated regulation of protein phosphatase 5

EMBO Journal, 2005
David Barford   +2 more
exaly  

Rearrangement of the Protein Phosphatase 1 Interactome During Heart Failure Progression

Circulation, 2018
Xander Wehrens   +2 more
exaly  

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics

Cell Systems, 2017
Markku Varjosalo   +2 more
exaly  

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