Results 11 to 20 of about 340,222 (317)

Amyloid precursor protein and amyloid precursor-like protein 2 in cancer

Oncotarget, 2016
Amyloid precursor protein (APP) and its family members amyloid precursor-like protein 1 (APLP1) and amyloid precursor-like protein 2 (APLP2) are type 1 transmembrane glycoproteins that are highly conserved across species. The transcriptional regulation of APP and APLP2 is similar but not identical, and the cleavage of both proteins is regulated by ...
Pandey, Poomy, Sliker, Bailee, Peters, Haley L., Tuli, Amit, Herskovitz, Jonathan, Smits, Kaitlin, Purohit, Abhilasha, Singh, Rakesh K., Dong, Jixin, Batra, Surinder K., Coulter, Donald W., Solheim, Joyce C.   +11 more
openaire   +3 more sources

ENTAIL: yEt aNoTher amyloid fIbrils cLassifier

BMC Bioinformatics, 2022
Background This research aims to increase our knowledge of amyloidoses. These disorders cause incorrect protein folding, affecting protein functionality (on structure).
Alessia Auriemma Citarella, Luigi Di Biasi, Fabiola De Marco, Genoveffa Tortora   +3 more
doaj   +1 more source

Computer-aided characteristics of proteins as potential precursors of bioactive peptides

Polimery, 2003
Proteins, apart from their basic functions, may play the role of precursors of the peptides that regulate the body functions and/or show anti­hypertensive, antithrombotic, antiamnestic, immunomodulating and other activities. Computer analysis of 109
Jerzy Dziuba
doaj   +1 more source

Impact of two neighbouring ribosomal protein clusters on biogenesis factor binding and assembly of yeast late small ribosomal subunit precursors.

PLoS ONE, 2019
Many of the small ribosomal subunit proteins are required for the stabilisation of late small ribosomal subunit (SSU) precursors and for final SSU rRNA processing in S. cerevisiae.
Jan Linnemann, Gisela Pöll, Steffen Jakob, Sébastien Ferreira-Cerca, Joachim Griesenbeck, Herbert Tschochner, Philipp Milkereit   +6 more
doaj   +1 more source

ELOVL4 protein preferentially elongates 20:5n3 to very long chain PUFAs over 20:4n6 and 22:6n3

Journal of Lipid Research, 2012
We hypothesized that reduction/loss of very long chain PUFAs (VLC-PUFAs) due to mutations in the ELOngase of very long chain fatty acid-4 (ELOVL4) protein contributes to retinal degeneration in autosomal dominant Stargardt-like macular dystrophy (STGD3 ...
Man Yu, Aaron Benham, Sreemathi Logan, R. Steven Brush, Md Nawajes A. Mandal, Robert E. Anderson, Martin-Paul Agbaga   +6 more
doaj   +1 more source

Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells. [PDF]

PLoS ONE, 2011
Prion diseases have been observed to deregulate the transcription of erythroid genes, and prion protein knockout mice have demonstrated a diminished response to experimental anemia.
Martin Panigaj, Hana Glier, Marcela Wildova, Karel Holada   +3 more
doaj   +1 more source

Structural transitions during large ribosomal subunit maturation analyzed by tethered nuclease structure probing in S. cerevisiae. [PDF]

PLoS ONE, 2017
Yeast large ribosomal subunit (LSU) precursors are subject to substantial changes in protein composition during their maturation due to coordinated transient interactions with a large number of ribosome biogenesis factors and due to the assembly of ...
Gisela Pöll, Christian Müller, Malena Bodden, Fabian Teubl, Norbert Eichner, Gerhard Lehmann, Joachim Griesenbeck, Herbert Tschochner, Philipp Milkereit   +8 more
doaj   +1 more source

The significant influence of residual feed intake on flavor precursors and biomolecules in slow-growing Korat chicken meat [PDF]

Animal Bioscience, 2021
Objective This study investigated the association between feed efficiency, physicochemical properties, flavor precursors and biomolecules in the thigh meat of Korat (KR) chickens.
Chotima Poompramun, Wittawat Molee, Kanjana Thumanu, Amonrat Molee   +3 more
doaj   +1 more source

Congenital Dyserythropoietic Anemia Type II: molecular analysis and expression of the SEC23B Gene

Orphanet Journal of Rare Diseases, 2011
Background Congenital dyserythropoietic anemia type II (CDAII), the most common form of CDA, is an autosomal recessive condition. CDAII diagnosis is based on invasive, expensive, and time consuming tests that are available only in specialized ...
Punzo Francesca, Bertoli-Avella Aida M, Scianguetta Saverio, Della Ragione Fulvio, Casale Maddalena, Ronzoni Luisa, Cappellini Maria D, Forni Gianluca, Oostra Ben A, Perrotta Silverio   +9 more
doaj   +1 more source

Targeting apoptotic anticancer response with natural glucosinolates from cell suspension culture of Lepidium sativum

Journal of Genetic Engineering and Biotechnology, 2023
Background Finding natural products with anticancer activity is an effective strategy to fight this disease. In this respect, Lepidium sativum or garden cress (family Brassicaceae) has been widely used worldwide for its wide therapeutic application ...
Mona M. Ibrahim, Marwa M. Mounier, Shawky A. Bekheet   +2 more
doaj   +1 more source