Results 21 to 30 of about 6,324,685 (356)
Chloroplast precursor protein translocon [PDF]
FEBS Letters, 1999 Chloroplasts are believed to have originated from a photosynthetic, prokaryotic ancestor. As the result of endosymbiotic evolution, most of the genes of the endocytobiont were displaced to the host nucleus. Today's chloroplasts must import most of their proteins from the cytosol as precursors.
Jürgen Soll, Timo May
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Enzymes in the Cholesterol Synthesis Pathway: Interactomics in the Cancer Context
Biomedicines, 2021 A global protein interactome ensures the maintenance of regulatory, signaling and structural processes in cells, but at the same time, aberrations in the repertoire of protein–protein interactions usually cause a disease onset.
Pavel Ershov +5 more
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The Role of Peptides Cleaved from Protein Precursors in Eliciting Plant Stress Reactions.
New Phytologist, 2020 As sessile organisms, plants are exposed to diverse abiotic and biotic stresses, and thus have developed complex signaling mechanisms that orchestrate multiple stress responses.
Ying-Lan Chen +3 more
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Functional requirements for a Samd14-capping protein complex in stress erythropoiesis
eLife, 2022 Acute anemia induces rapid expansion of erythroid precursors and accelerated differentiation to replenish erythrocytes. Paracrine signals—involving cooperation between stem cell factor (SCF)/Kit signaling and other signaling inputs—are required for the ...
Suhita Ray +7 more
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Recent Advances in Chemical Biology Using Benzophenones and Diazirines as Radical Precursors
Molecules, 2020 The use of light-activated chemical probes to study biological interactions was first discovered in the 1960s, and has since found many applications in studying diseases and gaining deeper insight into various cellular mechanisms involving protein ...
Muhammad Murtaza Hassan +1 more
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Molecules, 2022 This study explores utilization of a sustainable soybean by-product (okara) based on in silico approach. In silico approaches, as well as the BIOPEP database, PeptideRanker database, Peptide Calculator database (Pepcalc), ToxinPred database, and AllerTop
Andriati Ningrum +8 more
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Biology and pathophysiology of the amyloid precursor protein [PDF]
Molecular Neurodegeneration, 2011 The amyloid precursor protein (APP) plays a central role in the pathophysiology of Alzheimer's disease in large part due to the sequential proteolytic cleavages that result in the generation of β-amyloid peptides (Aβ). Not surprisingly, the biological properties of APP have also been the subject of great interest and intense investigations.
Zheng, Hui, Koo, Edward H
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Neuroprotective Secreted Amyloid Precursor Protein Acts by Disrupting Amyloid Precursor Protein Dimers [PDF]
Journal of Biological Chemistry, 2009 The amyloid precursor protein (APP) is implied both in cell growth and differentiation and in neurodegenerative processes in Alzheimer disease. Regulated proteolysis of APP generates biologically active fragments such as the neuroprotective secreted ectodomain sAPPalpha and the neurotoxic beta-amyloid peptide.
Gralle, M. +2 more
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The neuroendocrine polypeptide 7B2 is a precursor protein. [PDF]
Journal of Biological Chemistry, 1990 The neuroendocrine protein 7B2 is highly conserved and widely present in neurons and endocrine cells. It is coexpressed with the prohormone proopiomelanocortin (POMC) in the intermediate lobe of the pituitary gland of Xenopus laevis. To study the biosynthesis of 7B2 in this amphibian, an anti-7B2 monoclonal antibody was used in immunoprecipitation ...
Ayoubi, T.A. +6 more
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Медицинская иммунология, 2014 We studied the effect of a recombinant murine TNF (rmTNF) and TNF-binding protein of Variola virus (VARV-CrmB) upon colony-forming ability of bone marrow cells (BMC) from Balb/c mice.
L. B. Toporkova +3 more
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