Results 21 to 30 of about 340,222 (317)

Precursor Protein for Newcastle Disease Virus [PDF]

open access: yesJournal of Virology, 1973
The course of viral protein synthesis during infection of chicken embryo fibroblasts with Newcastle disease virus (NDV) L. Kansas has been followed by using sodium dodecyl sulfate polyacrylamide gel electrophoresis. Of the three major virion polypeptide molecular weight classes, I (78,400 daltons), II (53,500 daltons), and III (37,600 daltons), only II,
A C, Samson, C F, Fox
openaire   +2 more sources

The role of Dicer protein partners in the processing of microRNA precursors. [PDF]

open access: yesPLoS ONE, 2011
One of the cellular functions of the ribonuclease Dicer is to process microRNA precursors (pre-miRNAs) into mature microRNAs (miRNAs). Human Dicer performs this function in cooperation with its protein partners, AGO2, PACT and TRBP.
Edyta Koscianska   +2 more
doaj   +1 more source

Amyloid precursor protein processing and bioenergetics [PDF]

open access: yesBrain Research Bulletin, 2017
The processing of amyloid precursor protein (APP) to amyloid beta (Aβ) is of great interest to the Alzheimer's disease (AD) field. Decades of research define how APP is altered to form Aβ, and how Aβ generates oligomers, protofibrils, and fibrils. Numerous signaling pathways and changes in cell physiology are known to influence APP processing. Existing
Heather M. Wilkins, Russell H. Swerdlow
openaire   +2 more sources

Effects of Chickpea Protein on Carbohydrate Reactivity in Acrylamide Formation in Low Humidity Model Systems

open access: yesFoods, 2020
Asparagine and reducing sugars are the principal precursors of acrylamide in foods. Their main sources in pastries are flour and hen egg yolks. One method of reducing acrylamide content in food may be to add a chickpea protein preparation. The aim of the
Karolina Miśkiewicz   +2 more
doaj   +1 more source

Amyloid precursor protein and neural development [PDF]

open access: yesDevelopment, 2014
Interest in the amyloid precursor protein (APP) has increased in recent years due to its involvement in Alzheimer's disease. Since its molecular cloning, significant genetic and biochemical work has focused on the role of APP in the pathogenesis of this disease. Thus far, however, these studies have failed to deliver successful therapies. This suggests
Maya, Nicolas, Bassem A, Hassan
openaire   +2 more sources

Citrus psorosis virus 24K protein inhibits the processing of miRNA precursors by interacting with components of the biogenesis machinery

open access: yesMicrobiology Spectrum
Sweet orange (Citrus sinensis) is one of the most important fruit crops worldwide. Virus infections in this crop can interfere with cellular processes, causing dramatic economic losses. By performing RT-qPCR analyses, we demonstrated that citrus psorosis
Facundo E. Marmisolle   +7 more
doaj   +1 more source

Proteasomal degradation competes with Mia40-mediated import into mitochondria

open access: yesBMC Biology, 2018
Tandem fluorescent protein timers are elegant tools to determine proteolytic stabilities of cytosolic proteins with high spatial and temporal resolution. In a new study published in BMC Biology, Kowalski et al.
Eva Zöller   +2 more
doaj   +1 more source

Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane

open access: yesNature Communications, 2018
The mitochondrial TIM23-complex facilitates anterograde precursor transport across the inner membrane into the matrix and lateral release of precursors into the membrane.
Alexander Benjamin Schendzielorz   +7 more
doaj   +1 more source

Protocol for assessing the clogging of the mitochondrial translocase of the outer membrane by precursor proteins in human cells

open access: yesSTAR Protocols
Summary: Protein import into the mitochondria is required for organellar function. Inefficient import can result in the stalling of mitochondrial precursors inside the translocase of the outer membrane (TOM) and blockage of the mitochondrial entry gate ...
John Kim, Hilla Weidberg
doaj   +1 more source

Identification of General and Heart-Specific miRNAs in Sheep (Ovis aries).

open access: yesPLoS ONE, 2015
MicroRNAs (miRNAs or miRs) are small regulatory RNAs crucial for modulation of signaling pathways in multiple organs. While the link between miRNAs and heart disease has grown more readily apparent over the past three years, these data are primarily ...
Alessandro Laganà   +6 more
doaj   +1 more source

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