MOM19, an import receptor for mitochondrial precursor proteins [PDF]
, 1989 We have identified a 19 kd protein of the mitochondrial outer membrane (MOM19). Monospecific IgG and Fab fragments directed against MOM19 inhibit import of precursor proteins destined for the various mitochondrial subcompartments, including porin ...
Griffiths, Gareth +4 more
core +1 more source
Structural transitions during large ribosomal subunit maturation analyzed by tethered nuclease structure probing in S. cerevisiae. [PDF]
PLoS ONE, 2017 Yeast large ribosomal subunit (LSU) precursors are subject to substantial changes in protein composition during their maturation due to coordinated transient interactions with a large number of ribosome biogenesis factors and due to the assembly of ...
Gisela Pöll +8 more
doaj +1 more source
How proteins are transported into mitochondria [PDF]
, 1981 Most mitochondrial polypeptides are synthesized outside the organelle as precursors which are usually larger than the ‘mature’ polypeptides found within mitochondria.
Neupert, Walter, Schatz, Gottfried
core +1 more source
Computer-aided characteristics of proteins as potential precursors of bioactive peptides
Polimery, 2003 Proteins, apart from their basic functions, may play the role of precursors of the peptides that regulate the body functions and/or show antihypertensive, antithrombotic, antiamnestic, immunomodulating and other activities. Computer analysis of 109
Jerzy Dziuba
doaj +1 more source
ENTAIL: yEt aNoTher amyloid fIbrils cLassifier
BMC Bioinformatics, 2022 Background This research aims to increase our knowledge of amyloidoses. These disorders cause incorrect protein folding, affecting protein functionality (on structure).
Alessia Auriemma Citarella +3 more
doaj +1 more source
PLoS ONE, 2019 Many of the small ribosomal subunit proteins are required for the stabilisation of late small ribosomal subunit (SSU) precursors and for final SSU rRNA processing in S. cerevisiae.
Jan Linnemann +6 more
doaj +1 more source
Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage [PDF]
Proceedings of the National Academy of Sciences, 2004 Amyloid-β precursor protein (APP), a type I membrane protein, is physiologically processed by α- or β-secretases that cleave APP N-terminal to the transmembrane region. Extracellular α-/β-cleavage of APP generates a large secreted N-terminal fragment, and a smaller cellular C-terminal fragment.
Thomas C. Südhof, Angela Ho
openaire +3 more sources
Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells. [PDF]
PLoS ONE, 2011 Prion diseases have been observed to deregulate the transcription of erythroid genes, and prion protein knockout mice have demonstrated a diminished response to experimental anemia.
Martin Panigaj +3 more
doaj +1 more source
Mitochondrial protein import [PDF]
, 1989 Proteolytic degradation of receptor sites on the mitochondrial surface strongly reduces the efficiency of mitochondrial protein import. The remaining residual import still involves basic mechanisms of protein import, including: insertion of precursors ...
Neupert, Walter +2 more
core +4 more sources
Different Transport Pathways of Individual Precursor Proteins in Mitochondria [PDF]
, 1981 Transport of mitochondrial precursor proteins into mitochondria of Neurospora crassa was studied in a cellfree reconstituted system. Precursors were synthesized in a reticulocyte lysate programmed with Neurospora mRNA and transported into isolated ...
Allen E. H. +31 more
core +1 more source