Results 191 to 200 of about 215,450 (265)

Noncoding RNAs orchestrating the central dogma. [PDF]

J Biol Chem
Lozano-Villada S, Puthanveettil SV.
europepmc   +1 more source

Ultrasound‐Triggered Gelation for Restoring Biomechanical Properties of Degenerated Functional Spinal Units

Advanced Healthcare Materials, EarlyView.
This study introduces an innovative approach to treating intervertebral disc degeneration using ultrasound‐triggered in situ hydrogel formation. Proof‐of‐concept experiments using optimized biomaterial and ultrasound parameters demonstrate partial restoration of biomechanical function and successful integration into degenerated disc tissue, offering a ...
Veerle A. Brans, Anna P. Constantinou, Matthew J. Kibble, Valeria Nele, Daniel Reumann, Luca Bau, Sebastien J. P. Callens, James P. K. Armstrong, Nicolas Newell, Constantin C. Coussios, Molly M. Stevens, Michael D. Gray   +11 more
wiley   +1 more source

The emerging role of epigenetic regulation in pain sensitization associated with headache disorders. [PDF]

J Headache Pain
Tao Y, Cai X, Sun Y, Lu W, Wang S, Huang Z, Zhang Y, Tao J, Zhang Y.   +8 more
europepmc   +1 more source

Geometrically Tunable Scaffold‐Free Muscle Bioconstructs for Treating Volumetric Muscle Loss

Advanced Healthcare Materials, EarlyView.
Volumetric muscle loss is associated with traumatic muscle resulting in permanent functional impairment. Mold‐based, scaffold‐free, high‐density muscle tissue bioconstructs are developed in customizable geometric shapes and sizes. The transplanted rectangular solid‐shaped muscle bioconstructs improved muscle force recovery and tissue regeneration in ...
Bugra Ayan, Gaoxian Chen, Ishita Jain, Sha Chen, Gladys Chiang, Caroline Hu, Renato Reyes, Beu P. Oropeza, Ngan F. Huang   +8 more
wiley   +1 more source

Biomolecular condensates: molecular structure, biological functions, diseases, and therapeutic targets. [PDF]

Mol Biomed
Choi S, Lee JM, Kim KK.
europepmc   +1 more source

Modular Platform for Rapidly Investigating Long‐Distance Propagation of Human Neural Network Activity

Advanced Healthcare Materials, EarlyView.
This study presents the first human neural organoid culture model capable of rapidly exhibiting long‐distance neural network propagation, thus delivering a system to experimentally investigate large‐scale communication during normal and diseased states.
Megh Dipak Patel, Sailee Sham Lavekar, Ronak Jaisalmeria, Suki Oji, Jazmine Jayasi, Caroline Cvetkovic, Robert Krencik   +6 more
wiley   +1 more source

Rapid virus-free production of recombinant yellow fever virus envelope protein and its in-depth biophysical analysis. [PDF]

Sci Rep
Schelle L, Kuttenlochner W, Sanchez V, Steigenberger B, Finkl K, Schmid M, Douat C, Halldorsson E, Schubert M, Suppmann S.   +9 more
europepmc   +1 more source

A Patient‐Specific 3D Printed Carotid Artery Model Integrating Vascular Structure, Flow, and Endothelium Responses

Advanced Healthcare Materials, EarlyView.
This study introduces the first miniaturized, patient‐specific carotid artery model created via 3D printing using GelMA with embedded vascular cells. Combining CFD, PIV, and flow perfusion, the model replicates anatomically dependent hemodynamics and cellular responses.
Jorge A. Catano, Louis Jun Ye Ong, Mingyang Yuan, Yunkun Qu, Jessica Benitez, Prasad KDV Yarlagadda, Yi‐Chin Toh, Zhiyong Li   +7 more
wiley   +1 more source

Global phosphoproteome analysis identifies PeVYV P4-induced host protein phosphorylation changes that facilitate viral proliferation. [PDF]

BMC Plant Biol
Li S, Yang X, Zhang Y, Luo X, Zhang Z, OuYang X, Liu H, Chen Y, Xu Y, Ye X, Lei X, Zhang S, Liu Y.   +12 more
europepmc   +1 more source