Results 81 to 90 of about 508,657 (349)

Expression of a human cartilage procollagen gene (COL2A1) in mouse 3T3 cells. [PDF]

open access: yes, 1991
Expression in a recombinant system has been difficult to obtain for any of the major fibrillar collagens that require processing by eight or more post-translational enzymes.
Ala-Kokko, Leena   +5 more
core   +1 more source

Protein folding causes an arrest of preprotein translocation into mitochondria in vivo [PDF]

open access: yes, 1991
With vital yeast cells, a hybrid protein consisting of the amino- terminal third of the precursor to cytochrome b2 and of the entire dihydrofolate reductase was arrested on the import pathway into mitochondria.
Becker, Karin   +7 more
core   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Comprehensive analysis of human protein N-termini enables assessment of various protein forms

open access: yesScientific Reports, 2017
Various forms of protein (proteoforms) are generated by genetic variations, alternative splicing, alternative translation initiation, co- or post-translational modification and proteolysis.
Jeonghun Yeom   +4 more
doaj   +1 more source

Identification of Epstein-Barr virus replication proteins in Burkitt’s lymphoma cells [PDF]

open access: yes, 2015
The working model to describe the mechanisms used to replicate the cancer-associated virus Epstein-Barr virus (EBV) is partly derived from comparisons with other members of the Herpes virus family.
Almohammad, Rajei   +8 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Defying Death: A Multi-Omics Approach to Understanding Desiccation Tolerance and Senescence in Eragrostis nindensis

open access: yesPlants
Eragrostis nindensis is a resurrection grass capable of surviving near-complete desiccation. We compared non-senescent leaf tissue (NST) and senescent leaf tissue (ST) to investigate the cellular and molecular basis of desiccation tolerance and ...
Christine F. Madden   +6 more
doaj   +1 more source

Cellular electron microscopy imaging reveals the localization of the Hfq protein close to the bacterial membrane.

open access: yesPLoS ONE, 2009
BackgroundHfq is a bacterial protein involved in several aspects of nucleic acid transactions, but one of its best-characterized functions is to affect the post-transcriptional regulation of mRNA by virtue of its interactions with stress-related small ...
Elia Diestra   +3 more
doaj   +1 more source

Post-translational processing of the glycoproteins of lymphocytic choriomeningitis virus. [PDF]

open access: yes, 1990
Intracellular events in the synthesis, glycosylation, and transport of the lymphocytic choriomeningitis virus (LCMV) glycoproteins have been examined. We have shown by N-glycanase digestion that LCMV strain Arm-4 bears five oligosaccharides on GP-1 and ...
Buchmeier, MJ   +3 more
core  

Diversification of a protein kinase cascade: IME-2 is involved in nonself recognition and programmed cell death in Neurospora crassa. [PDF]

open access: yes, 2012
Kinase cascades and the modification of proteins by phosphorylation are major mechanisms for cell signaling and communication, and evolution of these signaling pathways can contribute to new developmental or environmental response pathways.
Bueche, Joanna A   +2 more
core   +2 more sources

Home - About - Disclaimer - Privacy