Results 91 to 100 of about 244,545 (310)
iScience, 2019 Summary: CCAAT enhancer-binding protein beta (C/EBPβ) is a pioneer transcription factor that specifies cell differentiation. C/EBPβ is intrinsically unstructured, a molecular feature common to many proteins involved in signal processing and epigenetics ...
Gunnar Dittmar +12 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Structural Studies of Catalysis and Processing in Galactose [PDF]
, 2007 The fungal copper containing enzyme galactose oxidase is one of the earliest examples of a protein derived radical cofactor. A covalent bond, formed between the active site cysteine and the Cc of a tyrosine act as a site for radical formation, allowing ...
Akumanyi, Nana
core
The functions of y-box binding proteins in caenorhabditis elegans [PDF]
, 2015 Members of the highly conserved family of Y-box binding proteins (YBPs) have a broad spectrum of functions in both transcriptional and post-transcriptional regulation of gene expression.
Arnold, Andreas
core +1 more source
BiologyUnderstanding gene expression requires integrating multiple regulatory layers, because transcript abundance does not necessarily correspond to translational activity or protein abundance.
Turki Turki, Y.-H. Taguchi
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
The synthesis and processing of pea legumin in saccharomyces cerevisiae [PDF]
, 1987 An expression vector utilising the promoter from the yeast phosphoglycerate kinase gene and a complete protein-encoding sequence, was used to direct the expression of the pea seed storage protein, legumin, in yeast (Sciccharomyces cerevisicie) .
Chieng, Hock Ming
core
Neurobiology of Disease, 2009 We have previously demonstrated aggregation of amyloid precursor protein (APP) and β-amyloid (Aβ) to dense plaque-like deposits in the thalamus of rats subjected to transient middle cerebral artery occlusion (MCAO).
Mikko Hiltunen +6 more
doaj +1 more source
Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach
FEBS Letters, EarlyView.The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring +3 more
wiley +1 more source
Protein folding on the ribosome studied using NMR spectroscopy [PDF]
, 2013 NMR spectroscopy is a powerful tool for the investigation of protein folding and misfolding, providing a characterization of molecular structure, dynamics and exchange processes, across a very wide range of timescales and with near atomic resolution.
Christodoulou, J +9 more
core +1 more source