Results 111 to 120 of about 1,074,296 (345)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Balkan Medical Journal, 2014 Background: Moyamoya syndrome associated with protein S deficiency is rarely encountered and is usually reported in paediatric cases with cerebral ischaemia.
Betül Çevik +3 more
doaj +1 more source
Protein S Deficiency and Pulmonary Embolism in Children: A Case Report and Review of Literature [PDF]
, 2021 Othman Rizk A Mishref
openalex +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Central retinal vein prethrombosis as an initial manifestation of protein S deficiency
São Paulo Medical JournalCONTEXT: Retinal vein thrombosis is most common in old people, and is often associated with systemic vascular disease. One of its rare systemic causes is protein S deficiency.
Paulo de Tarso Ponte Pierre-Filho +3 more
doaj +1 more source
Acute Reversal of Warfarin Therapy in Patient with Protein C and S Deficiency Presenting for Emergency Surgery [PDF]
The Indian Anaesthetists' Forum, 2010 This is a case report of a 19 year young male presented with swelling and blackening of right upper limb and abdominal pain since 10 days. He was a known case of protein C and protein S deficiency on warfarin therapy, with deranged coagulation parameters
Sananta kumar Dash +3 more
doaj
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Cerebral Venous Thrombosis and Acute Pulmonary Embolism following Varicella Infection
European Journal of Case Reports in Internal Medicine, 2019 Varicella infection is caused by varicella-zoster virus (VZV) and commonly presents as a self-limiting skin manifestation in children. VZV also causes cerebral arterial vasculopathy and antibody-mediated hypercoagulable states leading to thrombotic ...
Rashid Khan +4 more
doaj +1 more source
Free protein S deficiency: a possible association with cerebrovascular occlusion. [PDF]
, 1989 Ralph L. Sacco +4 more
openalex +1 more source