Results 101 to 110 of about 24,775,971 (291)
Cardiac transplantation in a patient with protein S deficiency
The Annals of Thoracic Surgery, 1999 Cardiac transplantation was successfully performed in a patient with end-stage ischemic cardiomyopathy and hereditary protein S deficiency who had undergone two previous coronary artery bypass graft procedures. Routine intraoperative heparinization and reversal with protamine was undertaken, and the antifibrinolytic agent aprotinin was infused ...
T B, Spanier +4 more
openaire +2 more sources
Bilateral simultaneous central retinal vein occlusion in protein S deficiency
, 2015 Case report: This article reports a case of bilateral simultaneous central retinal vein occlusion (CRVO) and protein S deficiency. The 27-year-old male patient presented with a sudden decrease in vision in both eyes.
Reichel C, +5 more
core +1 more source
Combined protein C and protein S deficiency with pregnancy [PDF]
, 2017 A 35 year old female patient, married since 8 years, G6P1L1SA4 was registered with our unit since 8th week of gestation. She was a known case of protein C and protein S deficiency diagnosed 7 years ago (thrombotic profile- protein C: 70% normal: 70-100%,
Chaudhari, Hemangi K. +3 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Protein S Deficiency: A Case Study.
, 1994 Protein S deficiency, a life-threatening defect in the body\u27s protective mechanism against activated coagulation, can result in recurrent or atypical patterns of thrombosis.
Diefenderfer, Sharon, RN, BSN +2 more
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Molecular diversity and thrombotic risk in protein S deficiency: the PROSIT study.
, 2005 PROSIT enrolled 79 protein S (PS) deficient families and found 38 genetic alterations in 53 probands. Of these, 23 mutations were selected for expression in vitro, to evaluate their role as possible causative mutations.
REZENDE SM +14 more
core
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Anticoagulant Treatment with Rivaroxaban in Severe Protein S Deficiency
, 2013 We report a case of a 6-year-old girl with severe protein S deficiency due to a homozygous mutation and recurrent episodes of skin necrosis. She developed purpura fulminans at birth and a catheter-related venous thrombosis complicated by massive ...
S. M. Passamonti +6 more
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source