Results 101 to 110 of about 15,453 (247)

Nitric oxide and glutathione impact the expression of iron uptake- and iron transport-related genes as well as the content of metals in A. thaliana plants grown under iron deficiency [PDF]

, 2012
Mounting evidence indicate that nitric oxide (NO) acts as a signaling molecule mediating iron deficiency responses through the up-regulation of the expression of iron uptake-related genes.
Dobrowolska, Grażyna, Szymańska, K
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

The Frequency of Heterozygous Protein C Deficiency and Heterozygous Protein S Deficiency in Both Normal and Cerebral Thrombotic Conditions [PDF]

Protein C and protein S activities were assayed in 508 healthy subjects and in 121 patients with cerebral thrombosis, and the frequencies of the congenital deficiencies of these physiological anticoagulant proteins were examined. In the healthy subjects,
Endo, Takeshi, Tamura, Kohji, Kobayashi, Isao, Kurihara, Atsushi, 53430, 53433, Ozawa, Hideyuki, 53434, 53431, Yazaki, Akihiko, 53432, Amemiya, Norihiko, 53437, Kume, Shoji, 53435, 53436, Hamaoka, Satomi, 53428, Mizoe, Asako, 53429   +19 more
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Thromboembolic Occlusion of Left Bracheal artery Protein-C and Protein-S Deficiency - A Case Report

, 1970
Protein-C and Protein-S deficiency states are responsible for 3-5% (Protein-C) and 2-3% (Protein-S) of patients with venous thrombosis. Some cases of arterial thrombosis have been reported. It occurs twice as often in female as in males.
GMM Hossain, KN Haque, M Anisuzzaman, QA Azad, MG Kibria, MZ Haque   +5 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Protein S Deficiency: A Case Study.

, 1994
Protein S deficiency, a life-threatening defect in the body\u27s protective mechanism against activated coagulation, can result in recurrent or atypical patterns of thrombosis.
Diefenderfer, Sharon, RN, BSN, Niznik, Christine H, RN, MSN, Matula, Patricia A, RN, MSN, CCRN, CVN   +2 more
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Protein S deficiency manifesting with cerebral arterial and venous thrombosis in a young female with kissing carotids phenomenon

Thrombosis Journal
Background Majority of people with “kissing carotids”, an anatomical variation of the cervical carotid arteries showing tortuosity, kinking or coiling and coming in proximity at the midline are asymptomatic.
Salvatore Ssemmanda
doaj   +1 more source