Results 111 to 120 of about 15,453 (247)
[Familial protein S deficiency].
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1994 Protein S deficiency is an autosomal dominant inherited disease. The authors describe a family in which 27 of the 52 members had a deficiency of S protein. Eight family members have suffered from thromboembolic disease.
R, Gerdts, T, Gundersen, O R, Odegaard
openaire +1 more source
Combined protein C and protein S deficiency with pregnancy
, 2017 A 35 year old female patient, married since 8 years, G6P1L1SA4 was registered with our unit since 8th week of gestation. She was a known case of protein C and protein S deficiency diagnosed 7 years ago (thrombotic profile- protein C: 70% normal: 70-100%,
Chaudhari, Hemangi K. +3 more
core +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Effect of frozen storage conditions on antithrombin protein C and protein S activity assay stability
Thrombosis JournalBackground Inherited antithrombin, protein C, and protein S deficiency increase the risk of venous thromboembolism. The presence of defects can be identified by clinical laboratory assays.
Houmei Feng +6 more
doaj +1 more source
Protein C and Protein S Deficiencies
, 2014 Protein C and protein S are vitamin K-dependent protein with natural anticoagulant properties that play a major role in the coagulation pathway. Protein C is activated by the thrombin/thrombomodulin complex. Activated protein C cleaves membrane-bound active factors V and VIII and inactivates them.
Sébastien Humbert, Philippe Humbert
openaire +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Skin necrosis complicated by warfarin-induced protein S deficiency
Journal of the Formosan Medical Association, 2014 Tse-Yuan Liaw, Chung-Hsing Chang
doaj +1 more source
DEFICIENCY OF PROTEIN S AND FACTOR V PRESENTING AS ISCHEMIC STROKE IN A 14 YEARS OLD BOY
National Journal of Medical Research, 2015 A 14 year old nondiabetic, nonhypertensive boy was admittedwith left sided hemiparesis. He has been diagnosed with ischemic stroke due to combined deficiency of protein S and factor V.Inherited thrombophiliadue to deficiencies of natural anticoagulants (
Subhashish Deb +4 more
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